Open Advanced Search

Log in
Enterprise Plans
Free Trial

Log in
Free Trial
Enterprise Plans
Browse
Features
Pricing

DeepDyve

Advanced Search

show/hide query preview

With all of the words or DOIs:

DeepDyve's default query mode: search by keyword or DOI.

With the exact phrase:

Require these words, in this exact order. Do not surround your terms in double-quotes ("") in this field.

With at least one of the words:

Find any of these words, separated by spaces

Without the words:

Exclude each of these words, separated by spaces

With words in the article title:

Search for these terms only in the title of an article

Published between the years:

With the following authors:

Most effective as: LastName, First Name or Lastname, FN

With words in the journal name:

Search for articles published in journals where these words are in the journal name

Reset filters

Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DeepDyve requires Javascript to function. Please enable Javascript on your browser to continue.

Bioinformatics and Computational Biology Solutions Using R and Bioconductor

Part of the Statistics for Biology and Health Book Series

Editors: Gentleman, Robert; Carey, Vincent J.; Huber, Wolfgang; Irizarry, Rafael A.; Dudoit, Sandrine

DOI: 10.1007/0-387-29362-0

ISBN: 978-0-387-25146-2

Publisher: Springer New York - Springer Journals

Jan 1, 2005

11 - 20 of 25 Chapters

LitStream

Analysis Overview

Carey, V. J.; Gentleman, R.

Pages: 183 –187

[Chapters in this part of the book address tasks common in the downstream analysis (after preprocessing) of high-dimensional data. The basic assumption is that preprocessing has led to a sample for which it is reasonable to make comparisons between samples or between feature-vectors assembled...
LitStream

Distance Measures in DNA Microarray Data Analysis

Gentleman, R.; Ding, B.; Dudoit, S.; Ibrahim, J.

Pages: 189 –208

[Both supervised and unsupervised machine learning techniques require selection of a measure of distance between, or similarity among, the objects to be classified or clustered. Different measures of distance or similarity will lead to different machine learning performance. The appropriateness...
LitStream

Cluster Analysis of Genomic Data

Pollard, K. S.; van der Laan, M. J.

Pages: 209 –228

[We provide an overview of existing partitioning and hierarchical clustering algorithms in R. We discuss statistical issues and methods in choosing the number of clusters, the choice of clustering algorithm, and the choice of dissimilarity matrix. We also show how to visualize a clustering result...
LitStream

Analysis of Differential Gene Expression Studies

Scholtens, D.; von Heydebreck, A.

Pages: 229 –248

[In this chapter, we focus on the analysis of differential gene expression studies. Many microarray studies are designed to detect genes associated with different phenotypes, for example, the comparison of cancer tumors and normal cells. In some multifactor experiments, genetic networks are...
LitStream

Multiple Testing Procedures: the multtest Package and Applications to Genomics

Pollard, K. S.; Dudoit, S.; van der Laan, M. J.

Pages: 249 –271

[The Bioconductor R package multtest implements widely applicable resampling-based single-step and stepwise multiple testing procedures (MTP) for controlling a broad class of Type I error rates. The current version of multtest provides MTPs for tests concerning means, differences in means, and...
LitStream

Machine Learning Concepts and Tools for Statistical Genomics

Carey, V. J.

Pages: 273 –292

[In this chapter, supervised machine learning methods are described in the context of microarray applications. The most widely used families of machine learning methods are described, along with various approaches to learner assessment. The Bioconductor interfaces to machine learning tools are...
LitStream

Ensemble Methods of Computational Inference

Hothorn, T.; Dettling, M.; Bühlmann, P.

Pages: 293 –311

[Prognostic modeling of tumor classes, disease status, and survival time based on information obtained from gene expression profiling techniques is studied in this chapter. The basic principles of ensemble methods like bagging, random forests, and boosting are explained. The application of those...
LitStream

Browser-based Affymetrix Analysis and Annotation

Smith, C. A.

Pages: 313 –326

[webbioc is a CGI-based interface to Bioconductor methods for preprocessing and analyzing Affymetrix data. It wraps up the functionality of a number of Bioconductor packages into a consistent environment that can be deployed for use by small groups or large departments. Without ever seeing a...
LitStream

Introduction and Motivating Examples

Gentleman, R.; Huber, W.; Carey, V. J.

Pages: 329 –336
LitStream

Graphs

Huber, W.; Gentleman, R.; Carey, V. J.

Pages: 337 –346

[In this chapter, we describe and discuss various definitions and algorithms for graphs, their representation, and uses. The presentation is formal and we leave references to software and usage for the later chapters. Our goal is to use graphs to explore, navigate, represent, and model biological...

results per page

Browse All eBooks

Features

Search and discover articles on DeepDyve, PubMed, and Google Scholar
Read the full-text of open access and premium content
Organize articles with folders and bookmarks
Collaborate on and share articles and folders

Info

Pricing
Enterprise Plans
Browse Journals & Topics
About DeepDyve

Help

Help
Publishers
Contact Us

Sign up for your 14-Day Free Trial Now!

Read and print from thousands of top scholarly journals.

System error. Please try again!

Continue with Facebook

By signing up, you agree to DeepDyve’s Terms of Service and Privacy Policy.

Already have an account? Log in

Save Article to Bookmarks

Bookmark this article. You can see your Bookmarks on your DeepDyve Library.

To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.

Subscribe to Journal Email Alerts

To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Follow a Journal

To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Our policy towards the use of cookies

All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.

cookie policy