41 - 48 of 48 Chapters
[Sir James Paget described the disease as follows: It begins in middle age or later, is very slow in progress, may continue for many years without influence on the general health, and may give no other trouble than those which are due to the changes of shape, size, and direction of the diseased...
[Sarcoidosis involves systemic inflammatory disorder with noncaseating granulomatous inflammation in affected organs. It commonly involves the lungs, eyes, skin, joints, lymph nodes, and upper respiratory tract. In the United States, prevalence of sarcoidosis is between 10 and 40 cases/100,000...
[Osteoarthritis is a common disease. This chapter will review a number of myths and pearls that will assist clinicians in treating this disease.]
[This chapter is divided into sections based upon the anatomic sites: shoulder, elbow, wrist, hand, coccyx, hip, knee, ankle, and foot. Before focusing on specific musculoskeletal regions, however, we provide one introductory Pearl and then some general comments on the performance of...
[Low back pain is the most common musculoskeletal complaint. An estimated 80% of the population will experience low back pain over the course of their lifetime. The surgical treatment of common lumbar disorders accounts for over $20 billion as hospital fees each year in the United States. The...
[The diagnosis of amyloidosis depends on finding deposits with congo red birefringence in affected tis-sue.These deposits comprise fibrils of highly ordered proteins or protein fragments that generally contain prominent ²-pleated sheet domains. Many proteins have regions that can aggregate into...
[The Ehlers—Danlos syndrome (EDS) comprises a clinically heterogeneous group of connective tissue diseases, the principal features of which result from generalized but variable tissue fragility. EDS is a congenital disorder, but the age of onset of symptoms varies from birth to the fifth or even...
[Osteonecrosis, literally “bone death,” is the loss of viable bone tissue Up to 10% of all hip replacement procedures in the U.S. are performed for osteonecrosis. Major risk factors for osteonecrosis include glucocor-ticoid use, alcohol, cigarette smoking, systemic lupus erythematosus (SLE),...
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