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Journal of Agricultural and Food Chemistry

Subject Areas: Agricultural and Biological Sciences (miscellaneous)
Publisher: American Chemical Society - American Chemical Society
ISSN: 1520-5118
SJR: 310

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Journal Article

Applications of Bioisosteres in the Design of Biologically Active Compounds

Meanwell, Nicholas A.

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.3c00765 pmid:36961953

The design of bioisosteres represents a creative and productive approach to improve a molecule, including by enhancing potency, addressing pharmacokinetic challenges, reducing off-target liabilities, and productively modulating physicochemical properties. Bioisosterism is a principle exploited...
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Journal Article

New Analytical Strategy for Bioaccessibility Evaluation of Bromine and Iodine from Edible Seaweeds

Scaglioni, Priscila T.; Balbinot, Fernanda P.; Rondan, Filipe S.; Novo, Diogo L. R.; Silva, Alisson A.; Mesko, Marcia F.

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c08541 pmid:36972393

A strategy for determining the bioaccessibility of bromine and iodine from edible seaweeds was proposed for the first time using microwave-induced combustion (MIC) and ion chromatography coupled to mass spectrometry (IC-MS) after in vitro digestion. The concentrations of bromine and iodine in...
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Journal Article

High-Density Balsamic Vinegar: Application of Stable Isotope Ratio Analysis to Determine Watering Down

Perini, Matteo; Pianezze, Silvia; Paolini, Mauro; Larcher, Roberto

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c08362 pmid:36880814

Balsamic vinegar of Modena (ABM) is a product obtained from concentrated grape must with the addition of wine vinegar. It can be adulterated with the addition of exogenous water. The official method EN16466-3, based on the analysis of the stable isotope ratio δ 18O of the water, is not...
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Journal Article

Mechanism of Carbon Skeleton Formation of 2,3,5-Trimethylpyrazine via a Conversion Reaction between Methylglyoxal and Glyoxal

Jiang, Wei; Wang, Xiaoyuan; Ma, YunJiao; Du, Ming; Wu, Chao; Xu, Xianbing

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c08745 pmid:36942552

Maillard flavor compounds, such as 2,3,5-trimethylpyrazine, have been frequently identified in thermally processed food products, such as popcorn and peanuts. However, the origin of the carbon atoms in 2,3,5-trimethylpyrazine has not been clearly elucidated. Herein, a model reaction showed that...
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Journal Article

Peptidoglycan-Targeting Staphylolytic Enzyme Lysostaphin as a Novel and Efficient Protease toward Glycine-Rich Flexible Peptide Linkers

Liu, Zhiqiang; Gong, Guoli; Li, Yanni; Xu, Qinfeng; Akimbekov, Nuraly; Zha, Jian; Wu, Xia

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.3c00189 pmid:36967580

Glycine-rich flexible peptide linkers have been widely adopted in fusion protein engineering; however, they can hardly be cleaved for the separation of fusion partners unless specific protease recognition sites are introduced. Herein, we report the use of the peptidoglycan-targeting...
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Journal Article

A Synthetic Microbial Community of Plant Core Microbiome Can Be a Potential Biocontrol Tool

Wang, Zhen; Hu, Xiaohu; Solanki, Manoj Kumar; Pang, Fei

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c08017 pmid:36946724

Microbes are accepted as the foremost drivers of the rhizosphere ecology that influences plant health in direct or indirect ways. In recent years, the rapid development of gene sequencing technology has greatly facilitated the study of plant microbiome structure and function, and various...
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Journal Article

Fumonisin B1 Biosynthesis Is Associated with Oxidative Stress and Plays an Important Role in Fusarium proliferatum Infection on Banana Fruit

Xie, Lihong; Yang, Qiuxiao; Wu, Yanfei; Xiao, Jianbo; Qu, Hongxia; Jiang, Yueming; Li, Taotao

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.3c00179 pmid:36947157

Fungal response to oxidative stress during infection on postharvest fruit is largely unknown. Here, we found that hydrogen peroxide (H2O2) treatment inhibited the growth of Fusarium proliferatum causing crown rot of banana fruit, confirmed by scanning electron microscopy (SEM) and transmission...
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Journal Article

Potential of Food Protein-Derived Bioactive Peptides against Sarcopenia: A Comprehensive Review

Zhu, Xiaoxue; Wang, Jing; Lu, Yujia; Zhao, Yuchen; Zhang, Na; Wu, Wei; Zhang, Yuhao; Fu, Yu

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c09094 pmid:36988097

Sarcopenia is an age-related progressive muscle disorder characterized by accelerated loss of muscle mass, strength, and function, which are important causes of physiological dysfunctions in the elderly. At present, the main alleviating method includes protein supplements to stimulate synthesis...
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Journal Article

Composition, ζ Potential, and Molar Mass Distribution of 20 Must and Wine Colloids from Five Different Cultivars Obtained during Four Consecutive Vintages

Seidel, L.; Albuquerque, W.; Happel, K.; Ghezellou, P.; Gand, M.; Spengler, B.; Zorn, H.; Will, F.; Schweiggert, R.

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.2c09048 pmid:36977334

Colloids are responsible for undesirable haze formation in wine. Here, we characterized 20 colloid batches after isolation by ultrafiltration of musts and wines from five cultivars obtained from four consecutive vintages. Polysaccharide and protein concentrations of the colloids ranged from 0.10...
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Journal Article

Identification of Fungal and Bacterial Denitrification Inhibitors Targeting Copper Nitrite Reductase

Kumar, Ashutosh; Matsuoka, Masaki; Matsuyama, Akihisa; Yoshida, Minoru; Zhang, Kam Y. J.

2023 Journal of Agricultural and Food Chemistry

doi:10.1021/acs.jafc.3c00896 pmid:36967599

The usage of nitrification inhibitors is one of the strategies that reduce or slow down the denitrification process to prevent nitrogen loss to the atmosphere in the form of N2O. Directly targeting microbial denitrification could be one of the mitigation strategies; however, until now little...

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