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The International Journal of Biological Markers

Subject Areas: Cancer Research
Publisher: SAGE Publications - SAGE
ISSN: 1724-6008
SJR: 42

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Journal Article

Ensuring efficient development of personalized medicine by addressing regulatory needs: What role can research infrastructures play?

Capone, Francesca; Morrow, David; Moretti, Franca

2023 The International Journal of Biological Markers

doi:10.1177/03936155231179981 pmid:37278002

Personalized Medicine is a novel medical practice that uses an individual's genetic profile to guide decisions made regarding the prevention, diagnosis, and treatment of disease. Knowledge of a patient's genetic profile is crucial to support doctors in selecting the proper therapy and administer...
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Journal Article

Effect of secretory DKK3 on circulating CD56bright natural killer cells in patients with liver cancer

Liu, Da-Hua; Wen, Gui-Min; Song, Chang-Liang; Xia, Pu

2023 The International Journal of Biological Markers

doi:10.1177/03936155231169796 pmid:37071578

BackgroundLiver cancer seriously threatens human health. Natural killer (NK) cells are an important part of the innate immune system and have strong anti-tumor ability. Immunotherapy based on NK cells has become a hot topic in the treatment of liver cancer.MethodsIn this study, we checked the...
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Journal Article

Analysis of systemic inflammatory and coagulation biomarkers in advanced cervical cancer: Prognostic and predictive significance

Li, Ningfeng; Zhang, Yan; Qu, Wenjie; Zhang, Chao; Ding, Zhaoxia; Wang, Linlin; Cui, Baoxia

2023 The International Journal of Biological Markers

doi:10.1177/03936155231163599 pmid:36927209

ObjectivePeripheral systemic inflammatory, nutritional, and coagulation biomarkers have prognostic and predictive value in various malignancies. We evaluated the prognostic and predictive roles of systemic inflammatory, nutritional, and coagulation biomarkers in the circulating blood of patients...
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Journal Article

Alterations of commensal microbiota are associated with pancreatic cancer

Chen, Tian; Li, Xuejiao; Li, Gaoming; Liu, Yun; Huang, Xiaochun; Ma, Wei; Qian, Chao; Guo, Jie; Wang, Shuo; Qin, Qin; Liu, Shanrong

2023 The International Journal of Biological Markers

doi:10.1177/03936155231166721 pmid:37017014

BackgroundDysbiosis commonly occurs in pancreatic cancer, but its specific characteristics and interactions with pancreatic cancer remain obscure.Materials and methodsThe 16S rRNA sequencing method was used to analyze multisite (oral and gut) microbiota characteristics of pancreatic cancer,...
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Journal Article

Pleural CEA, CA-15-3, CYFRA 21-1, CA-19-9, CA-125 discriminating malignant from benign pleural effusions: Diagnostic cancer biomarkers

Fazli Khalaf, Farzaneh; Asadi Gharabaghi, Mehrnaz; Balibegloo, Maryam; Davari, Hamidreza; Afshar, Samaneh; Jahanbin, Behnaz

2023 The International Journal of Biological Markers

doi:10.1177/03936155231158661 pmid:36942429

IntroductionThere is a need for a rapid, accurate, less-invasive approach to distinguishing malignant from benign pleural effusions. We investigated the diagnostic value of five pleural tumor markers in exudative pleural effusions.MethodsBy immunochemiluminescence assay, we measured pleural...
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Journal Article

Gleason Score-related MT1L as biomarker for prognosis in prostate adenocarcinoma and contribute to tumor progression in vitro

Liu, Lei; Li, Yaping; Tang, Shiying; Yang, Bin; Zhang, Qiming; Xiao, Ruotao; Hou, Xiaofei; Liu, Cheng; Ma, Lulin

2023 The International Journal of Biological Markers

doi:10.1177/03936155231156458 pmid:37192745

BackgroundThe Gleason Score is well correlated with biological behavior and prognosis in prostate adenocarcinoma (PRAD). This study was derived to determine the clinical significance and function of Gleason-Score-related genes in PRAD.MethodsRNA-sequencing profiles and clinical data were...
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Journal Article

MMR markers correlate with clinical outcome in patients with esophageal squamous cell carcinoma

Yamauchi, Takuro; Fujishima, Fumiyoshi; Tsunokake, Junichi; Kunimitsu, Atsushi; Akaishi, Ryujiro; Ozawa, Yohei; Fukutomi, Toshiaki; Okamoto, Hiroshi; Sato, Chiaki; Taniyama, Yusuke; Kamei, Takashi; Ichinohasama, Ryo; Sasano, Hironobu

2023 The International Journal of Biological Markers

doi:10.1177/03936155231165068 pmid:37009661

BackgroundThe DNA mismatch repair system is one of the defense mechanisms in the body, and the inactivation of mismatch repair plays a pivotal role in secondary carcinogenesis and progression. However, the significance of mismatch repair in esophageal squamous cell carcinoma (ESCC) has not been...

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