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Over the past 30 years, numerous neuroscientific studies involving both human and rodent subjects have investigated the brain regions and networks supporting path integration and sought to identify the underlying neural mechanisms. Although these studies contributed to an increased understanding...
The COVID-19 pandemic is an ongoing stressor that has resulted in the exacerbation of mental health problems worldwide. However, longitudinal studies that identify preexisting behavioral and neurobiological factors associated with mental health outcomes during the pandemic are lacking. Here, we...
Repetitive bouts of binge drinking can lead to neuroplastic events that alter ethanol’s pharmacologic effects and perpetuate excessive consumption. The corticotropin-releasing factor (CRF) system is an example of ethanol-induced neuroadaptations that drive excessive ethanol consumption. Our...
The medial frontal cortex (MFC) in rodents emits rhythmic activity that is entrained to the animal’s licking cycle during consumption and encodes the value of consumed fluids. These signals are especially prominent in the rostral half of the MFC. This region is located above an orbitofrontal...
Successful navigation depends critically upon two broad categories of spatial navigation strategies that include allocentric and egocentric reference frames, relying on external or internal spatial information, respectively. As with older adults, aged rats show robust impairments on a number of...
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