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Keratinocytes and fibroblasts have been grown onto a series of triblock copolymers based on 1,5-dioxepan-2-one (DXO) and L-lactide (LLA). The molar ratio of DXO and LLA were varied in the copolymers. This resulted in different degrees of...
In poly(DL-lactic acid)-cholesterol oligomers (LC), a novel cholesterol modified poly(DL-lactic acid) (PLA), was synthesized via bulk polymerization of DL-lactide using cholesterol initiator. Gel permeation chromatography (GPC) and 1H nuclear...
Using ultra-fine grain technology, a fast-setting type of carbonated hydroxyapatite (CHA) material from Ca3(PO4)2·3H2O (ACP), CaCO3, Ca(H2PO4)2 (MCPA) and Na3PO4 was prepared. The ultra-fine particles (3 m) shortens the setting time,...
Superoxide dismutase (SOD) was chemically modified with carboxymethylcellulose through two different synthetic procedures: Reductive alkylation with the periodate-oxidized polymer (SOD-CMCox), and the formation of amide linkages through a...
New polymers with antitumor activity were synthesized by conjugating ethyl p-aminobenzoate (benzocaine) and N-hydroxy-2,3-dihydroxybenzamide (Didox) onto carboxymethylcellulose (CMC) and oxidized CMC. The biological tests (in vitro and in vivo) for...
Therapeutic uses of a variety of drug carrier systems have significant impact on the treatment and potential cure of many chronic diseases, including cancer, diabetes, mellitus, rheumatoid arthritis, HIV infection, and drug addiction. Drug delivery...
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