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Chitosan/nano-hydroxyapatite membranes with negative charges were fabricated by grid-controlled constant voltage corona charging, and the charged membranes were investigated for cell biocompatibility and osteoinduction. The osteoblasts on the chitosan/nano-hydroxyapatite composite electret...
Composite scaffolds of poly(l-lactide acid) and hydroxyapatite are of great interest in bone tissue engineering, but their mechanical properties are typically inferior to scaffolds of pure poly(l-lactide acid) due to agglomeration of the particles and weak interfacial component interaction....
Amelogenin is a major enamel matrix protein onto which developing enamel forms. In the realm of tissue engineering, amelogenin has been studied and applied to periodontal and wound healing applications. This study introduces the first attempts of incorporating amelogenin within an electrospun...
Chitosan is soluble in acidic media, which makes it incompatible for the encapsulation of cells and pH-sensitive molecules. In this work, a mild chitosan-based system with two sequential gelation steps is proposed, where the model drug dexamethasone and L929 cells are immobilized inside hydrogel...
A hydrogel hybrid of chemically cross-linked hydroxyethyl acrylate interpenetrated with physically cross-linked carboxymethylcellulose was prepared as a superporous structure with swelling rates ranging from a few seconds to minutes depending on the swelling medium. A new method was adopted to...
The objective of this study was to develop a thermosensitive polyelectrostatic complex, based on polysaccharides, as carriers for long-term protein delivery. We developed a thermosensitive polyelectrostatic complex formed through combined electrostatic and hydrophobic interactions. The copolymer...
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