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Psychiatric disorders have become an increasing concern in the treatment of substance abusers. The introduction of the Human Immunodeficiency Virus (HIV) into this population has further complicated treatment. This study examines the prevalence of psychiatric disorders in an opioid dependent...
We review the controlled trials of antidepressant treatment in methadone patients. Several studies show antidepressant effects, but none demonstrate clear improvement in drug abuse. This is contrary to "self-medication" but rather suggests depression is either independent or substance induced....
Twenty-two methadone maintained opioid addicts with either depression or persistent cocaine use received open label fluoxetine in addition to their methadone. Fluoxetine significantly decreased depressive symptoms from pre-treatment to endpoint in subjects with depression, while its effect on...
Eight opioid-dependent individuals were maintained on daily sublingual buprenorphine (8 mg) for 28 days and assigned randomly to one of two outpatient detoxification schedules under double-blind, double-dummy conditions. The two detoxification schedules were buprenorphine gradual (36 days; N =...
In a 3 × 2 factorial design, 360 new admissions to methadone maintenance were randomly assigned to one of three levels of counseling: (1) ''medication only,'' (2) ''standard'' counseling, and (3) ''enhanced'' services; and one of two contingency contracting conditions: (1) no contingencies (NC),...
In a pilot study, 130 methadone maintained subjects with a six-month history of good treatment performance were assigned randomly, for a one-year study period, to an experimental condition (once per month non-random urine screen, counseling session and doctor visit, two times per month methadone...
There are several varieties of treatment facilities and modalities for dealing with substance abuse. In this study, the addition of acupuncture treatments to the usual care program at an existing county-based substance abuse treatment clinic was tested. Men and women who voluntarily attended the...
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