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Cocaine, mainly in the form of crack, continues to dominate New York City's illicit drug scene. Trends in cocaine-involved deaths, hospital emergencies, arrests and treatment admissions are reviewed from the late 1980s to the early 1990s. Also, street studies conducted at drug copping areas...
This study identifies factors that predict daily cocaine use among clients in a methadone maintenance program who participated in a cocaine treatment trial. Cocaine use decreased the longer clients remained in treatment, and the amount of cocaine used depended upon the day of the week, with...
This paper presents an overview of the quantitative electrophysiological (QEEG) research on cocaine dependence conducted at Brain Research Laboratories of New York University Medical Center. These studies have demonstrated that subjects with DSM-III-R cocaine dependence (without dependence on...
Analysis of the behavior of cocaine in the human brain with Positron Emission Tomography reveals that it is not only its affinity for the dopamine transporter that gives it its unique properties but also its fast pharmacokinetics. Its very fast uptake and clearance from the brain contrasts with...
Cocaine addiction and opiate addiction are both major health problems in the United States today. Perspective studies from our Laboratory, which were able to detect the advent of the HIV-1 epidemic in parental drug abusers in New York City beginning around 1978, also showed that, from the...
Twenty-three methadone-maintained individuals seeking admission into a cocaine study were interviewed using the Pattern- of-Drug-Use assessment. Sample characteristics included: 96% male, 91% Caucasian, and 36 ± 5 mean years of age. Mean methadone dose was 81 ± 20 mg. On average, subjects...
After a long and courageous battle with cancer, Richard Lane died in 1994. He had been a long-term heroin addict and spent 12 years in prisons. After commencing treatment with methadone, he began to work with other addicts and helped to start Man Alive, the first methadone program in...
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