1 - 10 of 22 articles
Subjective functioning of older people with schizophrenia is affected by perceived physical health, depressive symptoms, and cognitive impairment.
The presence of neuritic changes, preservation of pyramidal cell numbers, and of areal diminution of the parahippocampal white matter can best be explained by a dying-back neuropathy.
Further studies will be required to establish the diagnostic stability and outcome of very-late-onset schizophrenia-like psychosis in older black Caribbean migrants.
Impaired CDT performance in elderly patients with schizophrenia is not attributable to normal aging. Also, the CDT uniquely relates to an array of cognitive abilities in this population, validating its multicognitive character and implicating multiple brain regions. The CDT's tolerability...
Since clear and etiologically meaningful differentiation between these diagnostic categories is not possible, they should not be separated by artificial diagnostic criteria for research purposes. Rather, the whole “schizo-paranoid” spectrum should always be analyzed. As long as...
These results support the hypothesis that a condition characterized by psychiatric symptoms and no mood symptoms can begin in later life and that this disorder is not a precursor to dementia.
Cognitive change appears very similar in magnitude across older, poor-outcome patients with different baselines of cognitive impairment. In contrast, functional decline was limited to patients with lower levels of functioning at baseline. These findings suggest that cognitive thresholds for...
These findings suggest that there is a relationship between cerebrovascular disease severity and mortality among depressed patients. More studies, with larger sample sizes, comparing depressed patients and control subjects are needed to further elucidate this relationship.
Frontal behavior syndromes occurred with higher frequency in AD. Apathy and executive dysfunction were elevated both in mild-to-moderate and severe AD. Disinhibition was elevated only in severe AD. In AD, apathy was associated with difficulty in basic activities of daily living (ADL), whereas...
This study provides initial evidence that citalopram may be effective in reducing aberrant motor behaviors in AD. However, because of the potential biases of an open-label study, these findings need to be confirmed in a larger, controlled trial.
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