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Although β-adrenoceptor antagonists (β-blockers) have effects on metabolism via their mechanism as blockers of adrenergic stimulation, most interest in the metabolic effects of β-blockers is caused by their effect on glucose metabolism. Strict metabolic control and management of cardiovascular...
Patients with signs and symptoms of heart failure and a preserved left ventricular (LV) systolic function may have significant abnormalities in diastolic function. This condition is called diastolic heart failure (DHF) and is observed in about 40% of patients with chronic heart failure (CHF)....
Inflammation is known to have a pathogenic role in atherosclerosis and the genesis of acute coronary syndromes. The peroxisome proliferator-activated receptor (PPAR)-γ, which is expressed in many constituent cells of atheromatous plaques, inhibits the activation of several proinflammatory genes...
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