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BMC Cancer

Subject Areas: Cancer Research
Publisher: BioMed Central - Springer Journals
SJR: 139

Open Access

Journal Article

An eHealth symptom and complication management program for cancer patients with newly created ostomies and their caregivers (Alliance): a pilot feasibility randomized trial

Xu, Shenmeng; Tan, Xianming; Ma, Chunxuan; McElyea, Rebecca S.; Shieh, Karl; Stover, Angela M.; Smith, Angela; Stitzenberg, Karyn; Basch, Ethan; Song, Lixin

2023 BMC Cancer

doi:10.1186/s12885-023-10919-x pmid:37301841

BackgroundCancer patients with newly created ostomies face complications that reduce quality of life (QOL) and increase morbidity and mortality. This proof-of-concept study examined the feasibility, usability, acceptability, and initial efficacy of an eHealth program titled the “Patient Reported...
Open Access

Journal Article

LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer

Du, Zhipeng; Zhang, Fangxiao; Liu, Lei; Shen, Hui; Liu, Tingting; Jin, Jing; Yu, Nanxi; Wan, Zhijie; Wang, Hang; Hu, Xuguang; Chen, Yuanyuan; Cai, Jianming

2023 BMC Cancer

doi:10.1186/s12885-023-10593-z pmid:36755223

BackgroundRadiotherapy is an important treatment for lung cancer, mainly by triggering DNA double-strand breaks to induce cell death. Blocking DNA damage repair can increase the radiosensitivity of tumor cells. Recent studies have identified long noncoding RNAs as key regulators in DNA damage...
Open Access

Journal Article

Characterization of stemness features and construction of a stemness subtype classifier to predict survival and treatment responses in lung squamous cell carcinoma

Lai, Jinzhi; Lin, Xinyi; Zheng, Huangna; Xie, Bilan; Fu, Deqiang

2023 BMC Cancer

doi:10.1186/s12885-023-10918-y pmid:37291533

BackgroundCancer stemness has been proven to affect tumorigenesis, metastasis, and drug resistance in various cancers, including lung squamous cell carcinoma (LUSC). We intended to develop a clinically applicable stemness subtype classifier that could assist physicians in predicting patient...
Open Access

Journal Article

Dietary advanced glycation end products are associated with an increased risk of breast cancer in Iranian adults

Jahromi, Mitra Kazemi; Tehrani, Asal Neshatbini; Farhadnejad, Hossein; Emamat, Hadi; Ahmadirad, Hamid; Teymoori, Farshad; Heidari, Zeinab; Saber, Niloufar; Rashidkhani, Bahram; Mirmiran, Parvin

2023 BMC Cancer

doi:10.1186/s12885-023-11462-5

BackgroundDietary advanced glycation end products (AGEs) can play an important role in increasing inflammatory factors and oxidative stress as risk factors for cancers. In the present study, we aimed to assess the relationship between dietary AGEs and the risk of breast cancer (BC) in Iranian...
Open Access

Journal Article

Effects of preoperative albumin-to-globulin ratio on overall survival and quality of life in esophageal cell squamous carcinoma patients: a prospective cohort study

Zhang, Juwei; Lin, Zheng; Zhou, Jinsong; Huang, Yue; Chen, Siting; Deng, Yuan; Qiu, Minglian; Chen, Yuanmei; Hu, Zhijian

2023 BMC Cancer

doi:10.1186/s12885-023-10809-2 pmid:37055773

ObjectiveThis study aimed to investigate the effect of preoperative albumin-to-globulin ratio (AGR) on overall survival (OS) and health-related quality of life in patients with esophageal cell squamous carcinoma (ESCC).MethodsSerum albumin and globulin were measured within one week before...
Open Access

Journal Article

Potential of miR-181a-5p and miR-630 as clinical biomarkers in NSCLC

Simiene, Julija; Dabkeviciene, Daiva; Stanciute, Diana; Prokarenkaite, Rimvile; Jablonskiene, Valerija; Askinis, Renatas; Normantaite, Kamile; Cicenas, Saulius; Suziedelis, Kestutis

2023 BMC Cancer

doi:10.1186/s12885-023-11365-5 pmid:37697308

BackgroundThe development of drug resistance and high mortality rates are the major problems observed in non-small cell lung cancer (NSCLC). Biomarkers indicating and predicting disease development towards these unfavorable directions are therefore on high demand. Many studies have demonstrated...
Open Access

Journal Article

Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma

Zhang, Yize; Liang, Xue; Lian, Qinghai; Liu, Liwen; Zhang, Baoyu; Dong, Zihui; Liu, Kunpeng

2023 BMC Cancer

doi:10.1186/s12885-023-10987-z pmid:37464334

The accumulation of lipid droplets (LDs) in hepatocytes is the main pathogenesis in nonalcoholic fatty liver disease (NAFLD), which is also the key risk factor for the progression of hepatocellular carcinoma (HCC). LDs behaviors are demonstrated to be associated with HCC advancement, and are...
Open Access

Journal Article

Consensus guidelines for the management of HR-positive HER2/neu negative early breast cancer in India, SAARC region and other LMIC by DELPHI survey method

Parikh, Purvish; Babu, Govind; Singh, Randeep; Krishna, Vamshi; Bhatt, Amit; Bansal, Indu; Rajappa, Senthil; Sahoo, Tarini Prasad; Aggarwal, Shyam; Bapna, Ajay; Biswas, Ghanshyam; Somashekhar, SP; Bajpai, Jyoti; Maniar, Vashishtha; Desai, Sharad; Raja, T; Rath, Goura Kishor

2023 BMC Cancer

doi:10.1186/s12885-023-11121-9 pmid:37525142

BackgroundPrecise prognostication is the key to optimum and effective treatment planning for early-stage hormone receptor (HR) positive, HER2/neu negative breast cancer patients. Differences in the breast cancer incidence and tumor anatomical features at diagnosis, pharmacogenomics data between...
Open Access

Journal Article

Alternating electric fields can improve chemotherapy treatment efficacy in blood cancer cell U937 (non-adherent cells)

Homami, Elham; Goliaei, Bahram; Shariatpanahi, Seyed Peyman; Habibi-Kelishomi, Zahra

2023 BMC Cancer

doi:10.1186/s12885-023-11339-7 pmid:37700230

BackgroundRecent achievements in cancer therapy are the use of alternating electrical fields at intermediate frequencies (100–300 kHz) and low intensities (1–3 V/cm), which specifically target cell proliferation while affecting different cellular activities depending on the frequency...
Open Access

Journal Article

High HSPB1 expression predicts poor clinical outcomes and correlates with breast cancer metastasis

Huo, Qin; Wang, Juan; Xie, Ni

2023 BMC Cancer

doi:10.1186/s12885-023-10983-3 pmid:37268925

BackgroundHeat shock protein beta-1 (HSPB1) is a crucial biomarker for pathological processes in various cancers. However, the clinical value and function of HSPB1 in breast cancer has not been extensively explored. Therefore, we adopted a systematic and comprehensive approach to investigate the...

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