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Our results show that EGFR and k-ras mutation analysis, combined with chromosomal copy number profiling, can help in defining the relationship among different tumors in one patient.
Detection of common EGFR mutations seems to be useful for selecting patients with NSCLC who would likely benefit from gefitinib monotherapy.
The relationship between the H/T ratio and lymph node metastases was evaluated by HRCT in lung adenocarcinomas 3 cm or smaller in maximum dimension. The H/T ratio may provide useful information in deciding on limited resection for lung cancer in such cases.
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