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Some concerned over “cherry‐picking” of patients.
This month The AJT Report looks at how CMS regulations on transplantation outcome measures could affect which patients are selected to receive transplants, as well as new research that is re‐igniting the debate over timing of death.
Accurately predicting liver transplant outcomes is complicated by numerous variables with only some being captured by the UNOS/OPTN database limiting the usefulness of predictive statistical models. See also article by Rana et al in this issue on page 2537.
Down‐staging before liver transplant may not change the behavior of hepatocellular carcinoma beyond Milan criteria but it may select those with a more favorable biology. See also article by Ravaioli et al in this issue on page 2547.
It is unclear why such a large percentage of the pediatric list remains inactive for an extended period of time when deceased donors are available and the mortality on the list is high. See also article by Gillen et al in this issue on page 2600.
A recent pediatric pilot of rituximab for treatment of renal allograft rejections with B cell infiltrates is intriguing, but much more data and adequately powered clinical trials are needed to determine whether therapy is efficacious. See also article by Zarkhin et al in this issue on page 2607.
Children, especially those under 5 years of age, have the highest death rate on the transplant waiting list compared to any other age range. This article discusses the concept, supported by OPTN data, that there is an age range of small pediatric donors, which are almost exclusively transplanted...
The Centers for Medicare and Medicaid Services (CMS) has developed a set of regulations that spell out the Conditions of Participation (CoPs) for provider hospitals that wish to be certified (and thus eligible for reimbursement) by Medicare for transplant services. The American Society of...
The CMS provides their perspective and responds to some of the issues raised by the ASTS viewpoint.
The objective was to review the current state of knowledge and recommend future research directions related to long‐term outcomes for pediatric liver transplant recipients. A 1‐day Clinical Research Workshop on Improving Long‐Term Outcomes for Pediatric Liver Transplant Recipients was held on...
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