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This month “The AJT Report” takes a look at a new policy in the works for the U.S. organ allocation system, and reviews a lawsuit that challenges the constitutionality of NOTA's ban on compensation for bone marrow donors, which could influence solid organ donation policy.
While normothermic extracorporeal support is a promising alternative to reduce ischemic injury in DCD grafts, further clinical studies are needed to evaluate its true impact on outcomes. See article by Rojas‐Pena et al on page 1365.
Renal transplant patients should be managed by dermatologists to prevent and manage skin cancer, a common cause of morbidity and mortality in organ transplant patients. See article by Salgo et al on page 1385.
Editorial comment on the ethical concerns raised by Woodle, et al regarding a policy of preferentially allocating kidneys from non‐directed living donors to facilitate paired‐exchange and chain transplantation. See article by Woodle et al on page 1460.
Vaginal extraction of the kidney: the start of something new or only a case report? See article by Allaf et al on page 1473.
The Model for End‐Stage Liver Disease (MELD) score is widely used to prioritize patients for liver transplantation. One of the pitfalls of the MELD score is the interlaboratory variability in all three components of the score (INR, bilirubin, creatinine). The interlaboratory variability in the...
Natural killer (NK) cells have been characterized classically for their cytotoxicity against pathogen infected or stressed cells as well as for their role in monitoring the expression of self MHC I. However, the participation of NK cells in solid organ transplantation (SOT) is poorly defined due...
In 2001 valganciclovir was approved by the FDA for treatment of HIV associated retinitis and in 2003 for prevention of post transplant CMV. This review provides an update on the status of its use and areas of controversy: How long should prophylaxis be given?; What is the appropriate dose for...
Donors after cardiac death (DCD) could increase the organ pool. Data supports good long‐term renal graft survival. However, DCDs are <10% of deceased donors in the United States, due to delayed graft function, and primary nonfunction. These complications are minimized by extracorporeal support...
The high frequency of memory T cells present in primates is thought to represent a major barrier to tolerance induction in transplantation. Therefore, it is crucial to characterize these memory T cells and determine their functional properties. High numbers of memory T cells were detected in...
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