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This month, “The AJT Report” reviews a recent organ allocation error and the use of standardized surgical checklists to reduce the incidence of such preventable operative errors. Also this month, a look at an increase in registered organ donors in the United States.
This month's Literature Watch highlights new pathways falling outside of the typical acquired immune spectrum that hold promise to remedy immune maladies that are resistant to current therapeutics.
The immune system's propensity to promote lymphocyte proliferation and activation in response to lymphopenia has predictable characteristics that should be considered when immunosuppressive protocols are deployed. See article by Cherkassky et al on page 1388.
The New York City protocol for a trial of uncontrolled donation after circulatory determination of death, which includes measures to reestablish circulation to maintain organ perfusion, may create confusion and controversy around the declaration of death and pose a setback for organ donation and...
Do we care about gender differences in liver transplantation rates if there are no differences in wait‐list mortality? See article by Mathur et al on page 1435.
Calcineurin inhibitor‐free immunosuppression continues to be challenged by efficacy and safety problems. See article by Friman et al on page 1444.
Listing status awareness is a potentially modifiable mechanism that may lead to disparities in kidney transplant access. See brief communication by Gillespie et al on page 1522.
There has been increasing interest in the role played by B cells, plasma cells and their associated antibody in the immune response to an allograft, driven by the need to undertake antibody‐incompatible transplantation and evidence suggesting that B cells play a role in acute cellular rejection...
Brazil is a country with over 190 000 000 inhabitants and a health system composed of a large public, government managed system. Between 1999 and 2010 the number of deceased donors increased by 161%, from 3.8 to 9.9 pmp, and the number of solid organ transplants increased by 121%, from 2891 to...
New onset diabetes after transplantation (NODAT) is a major complication associated with solid‐organ transplantation, sharing many similarities with type 2 diabetes mellitus. While metformin is recommended as the antiglycemic agent of choice in the general population, guidelines...
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