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The Supreme Court s ruling on the Affordable Care Act allowed states to opt out of the law's Medicaid expansion. In this issue of “The AJT Report,” we look at how the expansion—and nonparticipation in the expansion—might impact the field of transplantation.
Experiments injecting pluripotent cells into blastocyst embryos open exciting possibilities for the generation of self‐specific organs in xenogeneic animals.
This editorial summarizes the problems associated with biopsy interpretation and its role in planning appropriate therapy for patients with resolving polyomavirus nephropathy. See article by Menter et al on page 1474.
The authors ask the question—why are so many potential donors refused when potential pediatric heart transplant recipients have the highest pretransplant mortality rate of any solid organ transplant group? See article by Easterwood et al on page 1484.
The mycophenolic acid (MPA) preparations are one of the most commonly used immunosuppressants in the United States. However, these agents carry a black box warning regarding their use during pregnancy due to an association with increased risk of miscarriage and congenital defects. To ensure that...
Qualitative studies remain relatively uncommon in the transplant literature but are an important approach contributing unique strengths in some areas of research. With the increased focus on patient‐centered research and decision‐making, it is timely to review qualitative research in the context...
Solid organ transplantation is encumbered by an increasing number of waitlisted patients unrequited by the current organ supply. Preclinical models suggest that advances in deceased donor management and treatment can increase the quantity and quality of organs available for transplantation....
In 2011, live donor transmission events involving Human Immunodeficiency Virus (HIV) and Hepatitis C virus (HCV) prompted consideration of changing the process of live donor testing and evaluation in the United States. Following CDC recommendations for screening all live donors with nucleic acid...
Donor‐specific immunological tolerance using high doses of bone marrow cells (BMCs) has been demonstrated in mixed chimerism‐based tolerance induction protocols; however, the development of graft versus host disease remains a risk. Here, we demonstrate that the co‐infusion of limited numbers of...
Bone marrow‐derived early endothelial progenitor cells (BM‐EPCs) are a clinical tool for enhancing revascularization. However, the therapeutic efficacy of co‐transplantation of BM‐EPC with islets has not been investigated. In this study, marginal mass islets were co‐transplanted with or without...
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