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Puerto Rico has long had a large supply of donor organs that, historically, were shipped to the mainland United States. This month's “AJT Report” takes a look at recent infrastructure growth in the commonwealth that has allowed for the development of a successful, self‐sustaining transplant...
A recent study reveals the presence of lymphatic vessels that transport both immune cells and lymph within the central nervous system, and has relevance for infectious and malignant complications occurring in immunosuppressed individuals.
This editorial summarizes the current clinical status of heart transplantation from donation after circulatory death donors and reviews a preclinical study that examines the impact of different perfusate temperatures on the recovery of these hearts during normothermic machine perfusion. See the...
The authors review the challenges that ensue when a busy United States transplant center adopts a policy of offering liver transplantation to carefully selected patients with life‐threatening severe alcoholic hepatitis. See page 841 for the article from Im et al.
Kidney donors incur significant costs by donating their kidney, which imposes a barrier to living kidney donation and should be mitigated. See also the article from Rodrigue et al on page 869.
Obesity is often associated with the development of adipose tissue (AT) inflammation, resulting in metabolic dysfunction and an increased risk for developing type 2 diabetes. It is also associated with multiple chronic diseases, including cardiovascular, liver, and kidney disease, and thus can...
Natural killer (NK) cells are highly heterogeneous innate lymphocytes with a diverse repertoire of phenotypes and functions. Their role in organ transplantation has been poorly defined due to conflicting clinical and experimental data. There is evidence that NK cells can contribute to graft...
The introduction of the Mayo End‐Stage Liver Disease score into the Organ Procurement and Transplantation Network (OPTN) deceased donor liver allocation policy in 2002 has led to a significant increase in the number of simultaneous liver–kidney transplants in the United States. Despite multiple...
The National Organ Transplant Act stipulates that deceased donor organs should be justly and wisely allocated based on sound medical criteria. Allocation schemes are consistent across the country, and specific policies are publicly vetted. Patient selection criteria are largely in the hands of...
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