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Oncology Letters Volume 8 Issue 5

Subject Areas: Cancer Research
Publisher: Spandidos Publications - Spandidos Publications
ISSN: 1792-1074
SJR: 63

LitStream

Journal Article

Salvage therapy with mitoxantrone, etoposide, bleomycin and dexamethasone for refractory or relapsed aggressive non-Hodgkin's lymphoma patients with a poor performance status or comorbidity

Lin, Xuede; Shi, Xi; Zeng, Wucha; Zheng, Min; Huang, Liming

2014 Oncology Letters

doi:10.3892/ol.2014.2517 pmid:25295084

The treatment of refractory or relapsed aggressive non-Hodgkin's lymphoma (NHL) in patients in a state of poor health is difficult due to their ineligibility to receive intensive salvage chemotherapy. In the present study, 16 refractory or relapsed aggressive NHL patients with a poor performance...
LitStream

Journal Article

Evaluating the various phases of cisplatin‑induced emesis in rats

Shi, Jun

2014 Oncology Letters

doi:10.3892/ol.2014.2506 pmid:25289087

Use of cisplatin as a chemotherapeutic agent causes acute and delayed emesis. Kaolin, saccharin solution and normal feed consumption have been evaluated as an index of cisplatin‑induced emesis in rats; however, the most preferable of these methods for evaluating the various phases of emesis...
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Journal Article

Picropodophyllin and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells

Tomizawa, Minoru; Shinozaki, Fuminobu; Motoyoshi, Yasufumi; Sugiyama, Takao; Yamamoto, Shigenori; Sueishi, Makoto

2014 Oncology Letters

doi:10.3892/ol.2014.2484 pmid:25289088

Resistance is one limitation of sorafenib in the treatment of hepatocellular carcinoma (HCC). Insulin-like growth factor-1 receptor (IGF-1R) is involved in cancer cell proliferation. To assess the potential synergistic antitumor effects of picropodophyllin (PPP), an IGF-1R inhibitor, HLF and...
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Journal Article

Expression of insulin-like growth factor-II mRNA-binding protein-3 as a marker for predicting clinical outcome in patients with esophageal squamous cell carcinoma

Takata, Akihiro; Takiguchi, Shuji; Okada, Kaoru; Takahashi, Tsuyoshi; Kurokawa, Yukinori; Yamasaki, Makoto; Miyata, Hiroshi; Nakajima, Kiyokazu; Mori, Masaki; Doki, Yuichiro

2014 Oncology Letters

doi:10.3892/ol.2014.2465 pmid:25295085

Insulin‑like growth factor‑II mRNA‑binding protein‑3 (IMP3) is an important factor in carcinogenesis, although its clinical significance in esophageal squamous cell carcinoma (ESCC) remains unknown. The present study investigated the associations between IMP3 expression and the...
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Journal Article

Erythropoietin production in renal cell carcinoma and renal cysts in autosomal dominant polycystic kidney disease in a chronic dialysis patient with polycythemia: A case report

Ito, Keiichi; Asano, Takako; Tominaga, Susumu; Yoshii, Hidehiko; Sawazaki, Harutake; Asano, Tomohiko

2014 Oncology Letters

doi:10.3892/ol.2014.2469 pmid:25295086

In patients undergoing chronic hemodialysis (HD), erythropoietin (EPO) production from the kidney generally decreases and renal anemia develops. Patients without anemia, but with high serum EPO (sEPO) levels are rare among HD patients. The current study presents the case of a 67‑year‑old female...
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Journal Article

Prostate cancer with cyst formation detected by whole body positron emission tomography/computed tomography: A case report

Kim, Hakushi; Shoji, Sunao; Tomonaga, Tetsuro; Shima, Masanori; Terachi, Toshiro; Uchida, Toyoaki

2014 Oncology Letters

doi:10.3892/ol.2014.2510 pmid:25295087

The present study reports a case of prostate adenocarcinoma with cyst formation. A 72‑year‑old male diagnosed with multiple lung metastases at a local clinic was referred to Tokai University Hachioji Hospital (Tokyo, Japan) for detection of a primary lesion. Whole body positron emission...
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Journal Article

Laparoscopic heminephrectomy of a horseshoe kidney with giant renal cell carcinoma: A case report

Qi, Xiaolong; Liu, Feng; Zhang, Qi; Zhang, Dahong

2014 Oncology Letters

doi:10.3892/ol.2014.2455 pmid:25289089

A 72‑year‑old male was diagnosed incidentally with a 7-cm renal tumor in the right moiety of a horseshoe kidney during a routine physical examination, and was treated with laparoscopic radical heminephrectomy. The surgical time was 153 min and the estimated blood loss was 150 ml. The patient was...
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Journal Article

Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Zhu, Ying; Mao, Changfei; Wu, Jianzhong; Li, Shuchun; Ma, Rong; Cao, Haixia; Ji, Minghua; Jing, Changwen; Tang, Jinhai

2014 Oncology Letters

doi:10.3892/ol.2014.2444 pmid:25289090

It has previously been reported that KU60019, as a highly effective radiosensitizer, inhibits the DNA damage response and blocks radiation‑induced phosphorylation of key ataxia telangiectasia mutated targets in human glioma cells. The present study investigated whether KU60019 affects cell...
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Journal Article

Enhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinoma

Jia, Nan; Li, Qing; Tao, Xiang; Wang, Jieyu; Hua, Keqin; Feng, Weiwei

2014 Oncology Letters

doi:10.3892/ol.2014.2437 pmid:25295088

Endometrial carcinoma is the second most common gynecological malignancy of the female genital tract worldwide. Enhancer of zeste homolog 2 (EZH2), a critical component of the polycomb repressive complex 2, has been found to be involved in multiple biological processes and is overexpressed in...
LitStream

Journal Article

High temperature hyperthermia treatment for canines exhibiting superficial tumors: A report of three cases

Takagi, Hidefumi; Azuma, Kazuo; Osaki, Tomohiro; Itoh, Norihiko; Nakazumi, Shinichi; Taura, Yasuho; Okamoto, Yoshiharu

2014 Oncology Letters

doi:10.3892/ol.2014.2496 pmid:25295089

High temperature hyperthermia (HTH) treatment has previously been demonstrated to suppress tumor growth in a tumor‑bearing rat model. In the present study, the effects of HTH therapy for the treatment of spontaneous tumors in canines was evaluated. In case 1, an 18‑year‑old female Papillon...

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