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Ferroptosis is a type of regulated cell death dependent on iron and reactive
oxygen species. Ferroptosis is distinct from other cell death modalities, including
apoptosis, autophagy and necrosis. Dysregulated ferroptosis has been implicated
in a number of...
Patients with cancer receiving doxorubicin‑based chemotherapy often have
to stop taking the drug due to its cardiotoxicity and therefore lose out on the
beneficial effects of its potent antitumor activity. Doxorubicin has been demonstrated
Ovarian cancer (OVAC) remains the most lethal gynecological malignancy;
it is ranked fifth among the most common types of cancer that affect women worldwide.
Several aspects of the disease, including molecular pathogenesis, epidemiology,
Soft tissue sarcomas (STS) are rare tumors; they do not even equate to 1%
of all malignant tumor cases. One‑fifth of all STS occur in the upper extremities,
where epithelioid sarcoma, synovial sarcoma, clear cell sarcoma and malignant
fibrohistiocytoma are the...
Dysregulated expression of long non‑coding RNA X‑inactive specific transcript
(lncRNA‑XIST) has been indicated in various cancer types. In the present study,
a meta‑analysis was conducted to evaluate the potential role of lncRNA‑XIST in
The aim of the present study was to examine the expression and clinical
significance of long non‑coding RNA (lncRNA)‑CCDC26 in patients with acute myeloid
leukemia (AML), and to investigate the potential functions of CCDC26. The Gene
Expression Omnibus database...
Hox transcript antisense RNA (HOTAIR) is a long non‑coding RNA (lncRNA)
that serves a key role in the pathogenesis of various types of cancer, including
pancreatic adenocarcinoma. However, the diagnostic and prognostic values of HOTAIR
Multidrug resistance (MDR) remains one of the major causes of suboptimal
outcome following therapy in head and neck squamous cell carcinoma (HNSCC). ATP‑binding
cassette (ABC) transporters are overexpressed in HNSCC, which contributes to the
limited effect of...
Triple‑negative breast cancer (TNBC) has a poorer outcome compared with
that of other subtypes of breast cancer, and the discovery of dysregulated microRNA
(miRNA) and their role in tumor progression has provided a new avenue for elucidating
Long non‑coding RNA (lncRNA) FLVCR1 antisense RNA 1 (FLVCR1‑AS1) serves
a crucial role in many types of cancer; however, to the best of our knowledge,
the biological effect of FLVCR1‑AS1 in cholangiocarcinoma (CCA) remains unclear.
The present study aimed to...
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