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Ovarian cancer is a common tumor of the reproductive system, and primarily
responds to cytoreductive surgery and cisplatin (DDP)‑based chemotherapy. However,
chemoresistance results in high ovarian cancer mortality. Therefore, the aim of
the present study was...
Numerous studies have established population pharmacokinetics (PPK) models
of sirolimus in various populations. However, a PPK model of sirolimus in Chinese
patients with pediatric kaposiform hemangioendothelioma (PKHE) has yet to be established;
Malignant tumors are among the most life‑threatening diseases in the world.
Although many different types of antitumor agents are available, severe side effects
and toxicity limit their applications. Myeloid‑derived suppressor cells (MDSCs)
Breast cancer is one of the major causes of female morbidity and mortality,
accounting for ~25% of the total cancer cases in women. Phosphatidylinositol‑4,5‑bisphosphate
3‑kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream
The present study aimed to investigate the biological role of the mitochondrial
GTPase mitofusin‑2 (MFN2) in bladder cancer. MFN2 mRNA expression in tumor and
paired adjacent non‑tumor tissues from 8 patients was investigated using reverse...
Long non‑coding RNA GATA6 antisense RNA 1 (lncRNA GATA6‑AS) is a recently
identified lncRNA that is involved in endothelial‑mesenchymal transition. The
present study aimed to investigate the involvement of GATA6‑AS in the progression
of mantle cell lymphoma...
Colorectal cancer (CRC) is a tumor that derives from the rectum or colon,
and colon adenocarcinoma (COAD) is the most common type of CRC. The present study
was performed to identify genes that serve critical roles in the survival of patients
Expression levels of Transformer 2 protein homolog beta (TRA2B) in patients
with endometrial carcinoma were assessed to investigate the impact of TRA2B on
endometrial carcinoma cells. Furthermore, we analyzed the expression of several
genes in the tissue...
Endometrial carcinoma (EC) is a common malignant neoplasm of the female
reproductive tract. The malignant degree of type II EC is much greater than that
of type I EC, usually presenting with a high recurrence rate and a poor prognosis.
Therefore, the present...
Synaptic cell adhesion molecules (SynCAMs) are single transmembrane proteins
that belong to the immunoglobulin superfamily of cell adhesion molecules. In the
present study, a decrease in SynCAM levels in ovarian tumor tissues compared with
normal tissues is...
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