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The aim of the present study was to investigate the differential biological
characteristics between cancer‑associated ﬁbroblasts (CAFs) and peri‑tumor ﬁbroblasts
(PTFs) in tongue squamous cell carcinoma (TSCC). The primary CAFs and PTFs from
TSCC were obtained...
Cervical cancer pathogenesis is regulated by numerous factors, including
microRNAs. MicroRNA 1246 (miR‑1246) has been shown to serve a role in cervical
cancer tumorigenesis. However, the mechanisms through which miR‑1246 exerts its
oncogenic effects are largely...
Evidence suggests that hepatitis C virus (HCV) infection is among the main
causes of hepatocellular carcinoma (HCC). In addition, HCV‑induced HCC (HCV‑HCC)
exhibits adverse clinical outcomes and limited therapeutic treatments are available
for this condition....
Glioblastoma has a poor prognosis and is one of the most lethal types of
cancer in the world. TP53 induced glycolysis regulatory phosphatase (TIGAR) is
upregulated in various types of cancer. Therefore, the present study investigated
the role of TIGAR in...
The effect of long non‑coding RNA (lncRNA) THOR on proliferation and migration
of colon cancer cells was investigated. Lentiviral vector expressing lncRNA THOR
shRNA was used to establish colon cancer SW620 lncRNA THOR knockdown cell line
Osteosarcoma (OS) mortality rate is increasing. Various microRNAs (miRNAs)
have been investigated in the pathological process of OS except for miR-744. Hence,
this research was designed to explore miR-744 function in OS. RT-qPCR and western
blot analysis were...
Colorectal cancer is a common gastrointestinal cancer ranking in third place
of all cancers. Downregulation of miR‑148a has been observed in many tumors, and
miR‑148a was found to be an oncogene in colorectal cancer. The aim of our study
was to investigate the...
Nasopharyngeal carcinoma (NPC) is the most common cancer type originating
in the nasopharynx, and varies notably from other cancer types of the head and
neck in its occurrence, causes, clinical behavior and treatment. Significant effort
has been made into...
In order to assess the metastatic potential of residual hepatocellular carcinoma
(HCC) following insufficient radiofrequency ablation (RFA) and to improve the
current animal model, an insufficient RFA orthotopic nude mouse model of HCC was
developed in the...
Cryptotanshinone inhibits the proliferative and colony formation abilities
of human non‑small cell lung cancer cells (NSCLCs). The present study reported
that signal transducer and activator of transcription 3 is not the only target
of cryptotanshinone during...
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