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Osteosarcoma (OS) is a bone tumor of mesenchymal origin, most frequently
occurring during the rapid growth phase of long bones, and usually located in
the epiphyseal growth plates of the femur or the tibia. Its most common feature
is genome disorganization,...
Positron emission tomography‑computed tomography (PET/CT) is an efficient
method for the diagnosis of various types of human cancer. Studies have demonstrated
that Gd2O3‑doped carbon‑11‑choline (GdCho) can be used as a contrast nanoparticle
for PET/CT in the...
Pleomorphic adenomas (PAs) of salivary glands are the most frequent entity
of solid parotid tumors. Nonetheless, their genetics is not yet well understood.
Thus, the current study characterized 14 PAs using a unique combination of cytogenetic,
Long non‑coding (lnc)RNA mortal obligate RNA transcript (MORT) is inhibited
in numerous types of cancer in humans, indicating its role as a tumor suppressor.
The present study demonstrated downregulation of lncRNA MORT in the tumor tissues
of patients with...
Colorectal cancer (CRC) is a major contributor to cancer‑associated mortality
in China and remains a vast challenge worldwide. Although the genetic basis of
CRC has been investigated, the uncommonly mutated genes in CRC remain unknown,
in particular in the...
The novel long non‑coding RNA NR2F2‑AS1 has been characterized as an oncogene
in lung cancer. The present study aimed to investigate the role of NR2F2‑AS1 in
nasopharyngeal carcinoma (NPC). The results demonstrated that expression of NR2F2‑AS1
Effect of dexmedetomidine on the cognitive function of patients undergoing
gastric cancer surgery by regulating the phosphoinositide 3-kinase (PI3K)/AKT
signaling pathway was investigated. A total of 110 patients who were diagnosed
and underwent radical...
Breast cancer (BC) is one of the most dangerous malignant diseases among
women. A growing amount of evidence has suggested that long non‑coding RNAs participate
in the development and progression of BC and may potentially serve as therapeutic
Survivin is a promising marker for the diagnosis of bladder cancer. The
accuracy and clinical value of urinary survivin mRNA expression were compared
with urine cytology, which is the standard diagnostic method for bladder cancer.
Cytokines play an important role in the development of tumors. The purpose
of the present study was to evaluate the mechanisms and cytokine level changes
after transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma
(HCC). The Short...
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