1 - 10 of 32 articles
Ferroptosis is a novel form of regulated cell death characterized by accumulated
lipid reactive oxygen species (ROS) and inactivation of glutathione peroxidase
4 (GPX4). The present study aimed to investigate the role of microRNA (miRNA/miR)‑15a
The vascular endothelial growth factor receptor (VEGFR) network contributes
to breast cancer pathogenesis and progression. Anlotinib is a highly potent multi‑target
tyrosine kinase inhibitor that has been previously shown to exert antitumor effects
Proteinuria is a dose‑limiting adverse effect of ramucirumab treatment,
which is an anti‑angiogenic agent that targets the human vascular endothelial
growth factor. The predictors of proteinuria have not been completely elucidated
and there is currently no...
Cutaneous melanoma is an aggressive malignant cancer associated with poor
prognosis. Identification of reliable biomarkers for predicting prognosis of melanoma
contributes to improved clinical outcome and disease management. Long non‑coding
RNAs (lncRNAs) serve...
Non‑small cell lung cancer (NSCLC) remains the most frequent malignancy
worldwide, and lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC)
represent two major subtypes. LINC00628 has been demonstrated to promote LUAD
progression; however, its...
Urothelial carcinoma (UC) is one of the most common cancer types of the
urinary tract. UC is associated with poor 5‑year survival rate, and resistance
to cisplatin‑based therapy remains a challenge for invasive bladder cancer treatment.
Therefore, there is an...
Oral squamous cell carcinoma (OSCC) has gradually become a global public
health issue in recent years. Therefore, the current study aimed to explore the
mechanism of OSCC development and to identify a potential target that may be used
in its treatment. The...
ETS variant transcription factor 4 (ETV4) is a common cancer‑promoting transcription
factor and its expression has been found to be significantly upregulated in glioblastoma
multiforme (GBM), as determined via analysis of the Gene Expression Profiling...
Desmoplastic malignant pleural mesothelioma (DMM) is a rare histological
variant of malignant pleural mesothelioma, which is a highly aggressive neoplasm
of the mesothelium. DMM is associated with distant metastases and short survival.
Effective treatments for...
Pancreatic ductal adenocarcinoma (PDAC) is extremely fatal and potential
biomarkers for precision medicine of patients with PDAC are yet to be elucidated.
Moreover, the clinical values of circular RNAs (circRNAs) in PDAC management are
yet to be investigated....
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