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The present study examined the radiosensitization induced by a heat shock
protein 90 inhibitor, N‑vinylpyrrolidone (NVP)‑AUY922, in CD133‑positive cells
in a hypoxic area of T98G spheroids. CD133‑positive cells that are induced in
the hypoxic microenvironment...
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor
of the human gastrointestinal tract. Small intestinal GISTs appear to be associated
with poorer prognosis and higher metastasis rate than gastric GISTs of the same
size and mitotic...
Breast cancer (BC) is a malignant disease and the most commonly diagnosed
cancer in women. Numerous studies have previously verified the important role
of long non‑coding RNAs in a number of biological processes in BC. In the present
study, analysis of The...
Endometrial carcinoma (EC) exhibits an extremely malignant biological behavior
and has a high mortality rate. EC has recently become one of the most lethal cancers
in women worldwide. E3 ubiquitin ligases play an important role in the biological
Subsequently to the publication of the above article, the authors have realized
that they made some errors during the assembly of Fig. 3A. First, one of the group
names, “soCon”, should have been written as “siCON”, which represents the control
Cold coagulation of the cervix for cervical intraepithelial neoplasia (CIN),
when compared with cervical excision, has previously demonstrated comparable cure
rates and a reduction in the rate of spontaneous preterm birth. In the present
report the healing...
Stereotactic body radiotherapy (SBRT) has attracted extensive attention
as an effective treatment for patients with early‑stage non‑small cell lung cancer.
However, the factors affecting prognosis after SBRT have not been fully elucidated.
The aim of the...
Tongue squamous cell carcinoma (SCC) is a most common type of oral cancer.
Due to its highly invasive nature and poor survival rate, the development of effective
pharmacological therapeutic agents is urgently required. Quercetin (3,3',4',5,7‑pentahydroxyflavone)...
Mediator complex subunit 12 (MED12) is a subunit of Mediator, a large multi‑subunit
protein complex that acts an important regulator of transcription. Specifically,
MED12 is an integral part of the kinase module of Mediator along with MED13, CyclinC
Serine/threonine protein phosphatase 2A (PP2A) is a protein that has a wide
range of biological functions. As prostate cancer progresses from hormone-sensitive
prostate cancer to castration‑resistant prostate cancer (CRPC), the expression
level of PP2A has been...
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