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PurposeThe present investigation was aimed at preparing ketoconazole cocrystals using phenolic acid coformers.MethodThe slow solvent evaporation method was used to prepare ketoconazole cocrystal. The results of the DSC study, SEM study, and PXRD study confirmed the formation of a new crystalline...
ObjectiveMost studies regarding acidifiers focused on their role in improving the dissolution performance of a drug by altering the pH of the microenvironment. However, in the current research work, the impact of four different acidifiers (citric acid, tartaric acid, succinic acid, adipic acid)...
PurposePsoriasis is characterized by moisture- and lipid-deficient skin with an elevated epidermal keratinocyte hyperproliferation rate due to diminished p53 levels. Topical therapy with available tacrolimus ointment in such cases is very limited, ensuing to its less penetrability (thickened...
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