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Cathepsin S (Cat S) is a protein expressed in some epithelial cells, which
appears to be associated with cancer metastasis and recurrence. The abnormal expression
of Cat S has been reported to be associated with the progression of certain types
The oncological benefit of pelvic lymph node dissection (PLND) for prostate
cancer (PCa) remains unclear. The therapeutic effect of PLND on the elimination
of microscopic metastases during radical prostatectomy (RP) for PCa was examined
in the current study. A...
The present study aimed to assess the suppressive effect of direct‑acting
antivirals (DAAs) on hepatocellular carcinoma (HCC) recurrence following curative
treatment, particularly compared with interferon (IFN)‑based therapy. Among 117 curative
The current study reports the case of multifocal ectopic thyroid tissues
in the breast. Ectopic thyroid tissue is an uncommon entity found not only in
the cysts of thyroglossal ducts, but also along the thyroglossal duct. The most
frequent location of this...
Male breast cancer occurs rarely, comprising <1% of breast cancers. Due
to the low incidence of male breast cancer, clinical trials of this disease are
lacking. Therefore, therapeutic strategies utilized in the management of female
breast cancer are often...
Adjuvant chemotherapy with capecitabine is frequently not completed due
to adverse events, including hand‑foot syndrome. A higher completion rate of capecitabine
by reduction of the side effects may improve disease‑free survival and quality
of life of affected...
Postoperative pancreatic fistula (POPF) is a common complication following
pancreatic resection. It leads to increased medical costs, and longer hospital
stays. However, the risk factors of POPF are still unclear, and therefore, this
urgent clinical issue...
Anaplastic thyroid cancer (ATC) is an orphan disease with extremely poor
prognosis. In particular, unresectable stage IVC ATC is extremely difficult to
treat and is associated with a survival of only a few months, even when treated
with irradiation and/or...
The present report describes a case in which teriparatide, which is widely
used to treat osteoporosis, may have accelerated the growth of an undiagnosed
pre‑existing bone tumor of the femur. A 76‑year‑old woman visited hospital with
pain in the right thigh...
A 55‑year‑old woman presented with chest and back pain of unknown cause.
Contrast‑enhanced computed tomography revealed two low‑density tumors, sized 4.6
and 4.4 cm, in the hepatic caudate and left inner lobes, respectively. There are
multiple enlarged lymph...
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