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Abstract Background Clinical, virologic and immunologic characteristics of Zika virus (ZIKV) infections in US patients are poorly defined. Methods US-subjects with suspected ZIKV infection were enrolled. Clinical data and specimens were prospectively collected for ZIKV RNA detection, and...
Abstract Background Chikungunya virus is an emerging mosquito-borne pathogen with a wide global distribution. With the severe morbidity that it causes, chikungunya virus is a major public health problem in the affected areas and poses a considerable risk for unaffected areas hosting competent...
Abstract Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS), closely related to rituximab. We describe a case of HBV-reactivation in a MS patient with resolved HBV infection, receiving ocrelizumab. HBV-reactivation was monitored with HBV-DNA and HBsAg...
Abstract Background Two million individuals with Chronic hepatitis B (CHB) in the United States are at risk for premature death due to liver cancer and cirrhosis. CHB can be prevented by vaccination and controlled with treatment. Methods We created a lifetime Markov model to estimate the...
Abstract Background There is limited empirical evidence on the relationship between hyperglycemia, TB comorbidity, and mortality in the context of HIV. We assessed whether hyperglycemia at enrollment to HIV care was associated with increased risk of all-cause mortality and whether this...
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