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npj Microgravity Volume 9 Issue 1

Subject Areas: Agricultural and Biological Sciences (miscellaneous)
Publisher: Nature Publishing Group UK - Springer Journals
SJR: 24

Open Access

Journal Article

Human development and reproduction in space—a European perspective

Jain, Varsha; Chuva de Sousa Lopes, Susana M.; Benotmane, Mohammed A.; Verratti, Vittore; Mitchell, Rod T.; Stukenborg, Jan-Bernd

2023 npj Microgravity

doi:10.1038/s41526-023-00272-5 pmid:36973260

This review summarises key aspects of the first reproductive and developmental systems Science Community White Paper, supported by the European Space Agency (ESA). Current knowledge regarding human development and reproduction in space is mapped to the roadmap. It acknowledges that sex and gender...
Open Access

Journal Article

Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice

Hanson, Andrea M.; Young, Mary H.; Harrison, Brooke C.; Zhou, Xiaolan; Han, H. Q.; Stodieck, Louis S.; Ferguson, Virginia L.

2023 npj Microgravity

doi:10.1038/s41526-022-00233-4 pmid:36646717

Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight. We utilized an anti-myostatin peptibody to evaluate how...
Open Access

Journal Article

Time-dependent unloading effects on muscle and bone and involvement of FNDC5/irisin axis

Sanesi, Lorenzo; Storlino, Giuseppina; Dicarlo, Manuela; Oranger, Angela; Zerlotin, Roberta; Pignataro, Patrizia; Suriano, Clelia; Guida, Gabriella; Grano, Maria; Colaianni, Graziana; Colucci, Silvia Concetta

2023 npj Microgravity

doi:10.1038/s41526-023-00251-w pmid:36658231

The identification of biomarkers and countermeasures to prevent the adverse effects on the musculoskeletal system caused by the absence of mechanical loading is the main goal of space biomedical research studies. In this study, we analyzed over 4 weeks of unloading, the modulation in the...
Open Access

Journal Article

Condensation heat transfer in microgravity conditions

Berto, Arianna; Azzolin, Marco; Bortolin, Stefano; Miscevic, Marc; Lavieille, Pascal; Del Col, Davide

2023 npj Microgravity

doi:10.1038/s41526-023-00276-1 pmid:37015948

In the present paper, a thorough review of the experimental and numerical studies dealing with filmwise and dropwise condensation under microgravity is reported, covering mechanisms both inside tubes and on plain or enhanced surfaces. The gravity effect on the condensation heat transfer is...
Open Access

Journal Article

Characterization of oscillation modes in levitated droplets using image and non-image based techniques

Brosius, Nevin; Livesay, Jason; Karpinski, Zachary; Singiser, Robert; SanSoucie, Michael; Phillips, Brandon; Narayanan, Ranga

2023 npj Microgravity

doi:10.1038/s41526-023-00254-7 pmid:36653374

The dynamics of levitated liquid droplets can be used to measure their thermophysical properties by correlating the frequencies at which normal modes of oscillation most strongly resonate when subject to an external oscillatory force. In two preliminary works, it was shown via electrostatic...
Open Access

Journal Article

Human behavior and performance in deep space exploration: next challenges and research gaps

Pagnini, Francesco; Manzey, Dietrich; Rosnet, Elisabeth; Ferravante, Denise; White, Olivier; Smith, Nathan

2023 npj Microgravity

doi:10.1038/s41526-023-00270-7 pmid:36997549

As space exploration missions move from low orbit to distant destinations, including the Moon and Mars, new psychological, behavioral, and team challenges will arise. This manuscript represents an up-to-date white paper developed by European experts invited by the European Space Agency (ESA),...

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