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Esophageal cancer (EC) is a common malignancy with a poor prognosis worldwide. There are two core pathways that repair double‐strand breaks, homologous recombination (HR) and non‐homologous end joining (NHEJ) and numerous proteins are recognized that affect the occurrence of HR and NHEJ. Altered...
Biologicals have become an integral part of cancer treatment both as therapeutic agents and as supportive care agents. It is important to know that biologics are large, complex molecular entities requiring extensive immunogenicity testing and pharmacovigilance strategies to ensure no immune...
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