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The earliest activity-based photoacoustic (PA) probes were developed as diagnostic agents for cancer. Since this seminal work over a decade ago that specifically targeted matrix metalloproteinase-2, PA instrumentation, dye platforms, and probe designs have advanced considerably, allowing for the...
The radical S-adenosylmethionine (rSAM) superfamily has become a wellspring for discovering new enzyme chemistry, especially regarding ribosomally synthesized and post-translationally modified peptides (RiPPs). Here, we report a compendium of nearly 15,000 rSAM proteins with high-confidence...
Hydrogels have been extensively researched for over 60 years for their limitless applications in biomedical research. In this study, porous hydrogel microparticles (PHMPs) made of poly(ethylene glycol) diacrylamide were investigated for their potential as a delivery platform for therapeutic...
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