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lnCAR: A Comprehensive Resource for lncRNAs from Cancer Arrays

lnCAR: A Comprehensive Resource for lncRNAs from Cancer Arrays Long noncoding RNAs (lncRNA) have emerged as promis- landscape of lncRNAs derived from reannotation of public ing biomarkers in cancer diagnosis, treatment, and prognosis. microarray data. Currently, lnCAR contains 52,300 samples Recent studies suggest that a large number of coding gene for differential expression analysis and 12,883 samples for expression microarray probes could be reannotated as survival analysis from 10 cancer types. lnCAR allows users to lncRNAs. Microarray, once the most cutting-edge high- interactively explore any annotated or novel lncRNAs. We throughput gene expression technology, has been used for believe lnCAR will serve as a valuable resource for the com- thousands of cancer studies and has brought invaluable munity focused on lncRNA research in cancer. resources for studying the functions of lncRNA in cancer development. However, a comprehensive lncRNA resource Significance: lnCAR, a new interactive tool of reannotated based on microarray data is still lacking. Here, we present public cancer-related microarray data, provides expression lnCAR (lncRNAs from cancer arrays), a comprehensive open profiles and prognostic landscapes of lncRNAs across thou- resource for providing expression profiles and prognostic sands of samples and multiple cancer types. with RNA expression and clinical variables (e.g., tumor Introduction status, survival information). To fill these http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Research American Association of Cancer Research

lnCAR: A Comprehensive Resource for lncRNAs from Cancer Arrays

lnCAR: A Comprehensive Resource for lncRNAs from Cancer Arrays

Cancer Research , Volume 79 (8) – Apr 15, 2019

Abstract

Long noncoding RNAs (lncRNA) have emerged as promis- landscape of lncRNAs derived from reannotation of public ing biomarkers in cancer diagnosis, treatment, and prognosis. microarray data. Currently, lnCAR contains 52,300 samples Recent studies suggest that a large number of coding gene for differential expression analysis and 12,883 samples for expression microarray probes could be reannotated as survival analysis from 10 cancer types. lnCAR allows users to lncRNAs. Microarray, once the most cutting-edge high- interactively explore any annotated or novel lncRNAs. We throughput gene expression technology, has been used for believe lnCAR will serve as a valuable resource for the com- thousands of cancer studies and has brought invaluable munity focused on lncRNA research in cancer. resources for studying the functions of lncRNA in cancer development. However, a comprehensive lncRNA resource Significance: lnCAR, a new interactive tool of reannotated based on microarray data is still lacking. Here, we present public cancer-related microarray data, provides expression lnCAR (lncRNAs from cancer arrays), a comprehensive open profiles and prognostic landscapes of lncRNAs across thou- resource for providing expression profiles and prognostic sands of samples and multiple cancer types. with RNA expression and clinical variables (e.g., tumor Introduction status, survival information). To fill these

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References (35)

Publisher
American Association of Cancer Research
Copyright
©2019 American Association for Cancer Research.
ISSN
0008-5472
eISSN
1538-7445
DOI
10.1158/0008-5472.CAN-18-2169
Publisher site
See Article on Publisher Site

Abstract

Long noncoding RNAs (lncRNA) have emerged as promis- landscape of lncRNAs derived from reannotation of public ing biomarkers in cancer diagnosis, treatment, and prognosis. microarray data. Currently, lnCAR contains 52,300 samples Recent studies suggest that a large number of coding gene for differential expression analysis and 12,883 samples for expression microarray probes could be reannotated as survival analysis from 10 cancer types. lnCAR allows users to lncRNAs. Microarray, once the most cutting-edge high- interactively explore any annotated or novel lncRNAs. We throughput gene expression technology, has been used for believe lnCAR will serve as a valuable resource for the com- thousands of cancer studies and has brought invaluable munity focused on lncRNA research in cancer. resources for studying the functions of lncRNA in cancer development. However, a comprehensive lncRNA resource Significance: lnCAR, a new interactive tool of reannotated based on microarray data is still lacking. Here, we present public cancer-related microarray data, provides expression lnCAR (lncRNAs from cancer arrays), a comprehensive open profiles and prognostic landscapes of lncRNAs across thou- resource for providing expression profiles and prognostic sands of samples and multiple cancer types. with RNA expression and clinical variables (e.g., tumor Introduction status, survival information). To fill these

Journal

Cancer ResearchAmerican Association of Cancer Research

Published: Apr 15, 2019

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