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Reply: REPLY: provided us with additional confidence in the quantitative valid- ity of our measurements. e thank Ribarich et al for their interest in our work and Ribarich et al noted that 2 patients with AMD had only 1 eye Wthank the editors of AJNR for giving us the opportunity to affected by AMD and suggested a new analysis of our data that respond to this letter. Dialogues such as this are an important may be helpful to understand whether vascular changes occur part of healthy scientific discourse and progress, and we hope before or after the development of AMD. This observation does that our responses can help clarify several points of our article not appear to be a criticism per se, and we agree that this sug- and thereby help strengthen our study. gested analysis based on n ¼ 2 subjects should not be overinter- Ribarich et al noted that our patients with age-related macular preted. In reviewing our data for this response letter, we realized degeneration (AMD) and control groups were not perfectly age- that 1 of the eyes that we reported was excluded from analysis matched, but this was addressed in our description of the statistical due http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

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Publisher
American Journal of Neuroradiology
Copyright
© 2022 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.a7717
Publisher site
See Article on Publisher Site

Abstract

REPLY: provided us with additional confidence in the quantitative valid- ity of our measurements. e thank Ribarich et al for their interest in our work and Ribarich et al noted that 2 patients with AMD had only 1 eye Wthank the editors of AJNR for giving us the opportunity to affected by AMD and suggested a new analysis of our data that respond to this letter. Dialogues such as this are an important may be helpful to understand whether vascular changes occur part of healthy scientific discourse and progress, and we hope before or after the development of AMD. This observation does that our responses can help clarify several points of our article not appear to be a criticism per se, and we agree that this sug- and thereby help strengthen our study. gested analysis based on n ¼ 2 subjects should not be overinter- Ribarich et al noted that our patients with age-related macular preted. In reviewing our data for this response letter, we realized degeneration (AMD) and control groups were not perfectly age- that 1 of the eyes that we reported was excluded from analysis matched, but this was addressed in our description of the statistical due

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Dec 1, 2022

References

  • Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors
    KL. Pennington; MM. DeAngelis
  • Hypertension, Cardiovascular Disease, and Age-Related Macular Degeneration
    L. Hyman; AP. Schachat; Q. He
  • The association of cardiovascular disease with the long-term incidence of age-related maculopathy: The Beaver Dam eye study
    R. Klein; BEK. Klein; SC. Tomany
  • Subretinal drusenoid deposits and soft drusen: are they markers for distinct retinal diseases?
    RJ. Thomson; J. Chazaro; O. Otero-Marquez
  • Blood flow of ophthalmic artery in healthy individuals determined by phase-contrast magnetic resonance imaging
    K. Ambarki; P. Hallberg; G. Jóhannesson