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Response to “Flow Diversion in the Treatment of Intracranial Aneurysms: A Pragmatic Randomized Care Trial”

Response to “Flow Diversion in the Treatment of Intracranial Aneurysms: A Pragmatic Randomized... LETTERS Response to “Flow Diversioninthe Treatment of Intracranial Aneurysms: A Pragmatic Randomized Care Trial” ith great interest, we read the article by Raymond et al, mRS , 3 and complete or near-angiographic occlusion) between Wwhich described the results of the Flow Diversion in the FD and ASMO therapies. This difference was driven by a higher Treatment of Intracranial Aneurysms Trial. This parallel-group, rate of complete angiographic occlusion in the FD group. This is pre-randomized, controlled, open-label, all-inclusive, pragmatic problematic because the patients in the ASMO group were care trial included 278 patients from 3 centers in Canada during allowed to be treated conservatively and were consequently 10 years (2011–2020). In this study, patients who underwent scored with “incomplete occlusion.” This feature has created an flow diversion (FD) had significantly fewer poor outcomes than imbalance between study groups and complicates the interpreta- patients receiving alternative standard management options tion of the results. Alternatively, it would have been more in- (ASMO; relative risk, 0.68; 95% CI, 0.50–0.92). The authors con- formative to limit inclusion to patients who actually received cluded, “For patients with mostly unruptured, large, anterior aneurysm treatment. circulation (carotid) aneurysms, FD was more effective than the Last, to investigate http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Response to “Flow Diversion in the Treatment of Intracranial Aneurysms: A Pragmatic Randomized Care Trial”

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Publisher
American Journal of Neuroradiology
Copyright
© 2023 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.a7718
Publisher site
See Article on Publisher Site

Abstract

LETTERS Response to “Flow Diversioninthe Treatment of Intracranial Aneurysms: A Pragmatic Randomized Care Trial” ith great interest, we read the article by Raymond et al, mRS , 3 and complete or near-angiographic occlusion) between Wwhich described the results of the Flow Diversion in the FD and ASMO therapies. This difference was driven by a higher Treatment of Intracranial Aneurysms Trial. This parallel-group, rate of complete angiographic occlusion in the FD group. This is pre-randomized, controlled, open-label, all-inclusive, pragmatic problematic because the patients in the ASMO group were care trial included 278 patients from 3 centers in Canada during allowed to be treated conservatively and were consequently 10 years (2011–2020). In this study, patients who underwent scored with “incomplete occlusion.” This feature has created an flow diversion (FD) had significantly fewer poor outcomes than imbalance between study groups and complicates the interpreta- patients receiving alternative standard management options tion of the results. Alternatively, it would have been more in- (ASMO; relative risk, 0.68; 95% CI, 0.50–0.92). The authors con- formative to limit inclusion to patients who actually received cluded, “For patients with mostly unruptured, large, anterior aneurysm treatment. circulation (carotid) aneurysms, FD was more effective than the Last, to investigate

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Jan 1, 2023

References

  • Flow diversion in the treatment of intracranial aneurysms: a pragmatic randomized care trial
    J. Raymond; D. Iancu; W. Boisseau
  • Instrumental variable analysis to estimate treatment effects: a simulation study showing potential benefits of conditioning on hospital
    IE. Ceyisakar; N. van Leeuwen; EW. Steyerberg
  • Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study
  • Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study