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Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases

Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older... ORIGINAL CONTRIBUTION Scan for Author Audio Interview Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases Jie Zhang, PhD Context Based on limited data, the live attenuated herpes zoster (HZ) vaccine is con- Fenglong Xie, MS traindicated in patients taking anti–tumor necrosis factor (anti-TNF) therapies or other biologics commonly used to treat immune-mediated diseases. The safety and effec- Elizabeth Delzell, ScD tiveness of the vaccine are unclear for these patients. Lang Chen, PhD Objective To examine the association between HZ vaccination and HZ incidence within Kevin L. Winthrop, MD, MPH and beyond 42 days after vaccination in patients with selected immune-mediated dis- eases and in relation to biologics and other therapies used to treat these conditions. James D. Lewis, MD, MSCE Design, Setting, and Patients Retrospective cohort study of 463 541 Medicare Kenneth G. Saag, MD, MSc beneficiaries 60 years and older with rheumatoid arthritis, psoriasis, psoriatic arthritis, John W. Baddley, MD, MSPH ankylosing spondylitis, or inflammatory bowel disease using Medicare claims data from Jeffrey R. Curtis, MD, MS, MPH January 1, 2006, through December 31, 2009. Main Outcome Measures Herpes zoster incidence rate within 42 days after vac- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases

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References (32)

Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2012.7304
pmid
22760290
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Scan for Author Audio Interview Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases Jie Zhang, PhD Context Based on limited data, the live attenuated herpes zoster (HZ) vaccine is con- Fenglong Xie, MS traindicated in patients taking anti–tumor necrosis factor (anti-TNF) therapies or other biologics commonly used to treat immune-mediated diseases. The safety and effec- Elizabeth Delzell, ScD tiveness of the vaccine are unclear for these patients. Lang Chen, PhD Objective To examine the association between HZ vaccination and HZ incidence within Kevin L. Winthrop, MD, MPH and beyond 42 days after vaccination in patients with selected immune-mediated dis- eases and in relation to biologics and other therapies used to treat these conditions. James D. Lewis, MD, MSCE Design, Setting, and Patients Retrospective cohort study of 463 541 Medicare Kenneth G. Saag, MD, MSc beneficiaries 60 years and older with rheumatoid arthritis, psoriasis, psoriatic arthritis, John W. Baddley, MD, MSPH ankylosing spondylitis, or inflammatory bowel disease using Medicare claims data from Jeffrey R. Curtis, MD, MS, MPH January 1, 2006, through December 31, 2009. Main Outcome Measures Herpes zoster incidence rate within 42 days after vac-

Journal

JAMAAmerican Medical Association

Published: Jul 4, 2012

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