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T-suppressor circuits show many similarities to conventional positive immune responses. They are no more complicated than effector systems Abbreviations used in this chapter : ABA, azobenzenearsonate; Ag, antigen; Con A, concanavalin A; DNP, dinitrophenyl; FcR, receptor for Fc of immunoglobulin; GT, GAT, copolymers of glutamic acid and tyrosine and glutamic acid, tyrosine, and alanine; IL-2, interleukin 2; KLH, keyhole limpet hemocyanin; MHC, major histocompatibility complex; LDH, lactate dehydrogenase; NP, 4-hydroxy-3-nitrophenylacetyl; PSA, picrylsulfonic acid, 2,4,6-trinitrobenzenesulfonic acid; T-acc, T-acceptor cell; Th, T-helper cell; ThF, antigen specific T-helper factor; TMA, phenyltrimethylammonium; TNP, trinitrophenyl or picryl; Ts, T-suppressor cell; TsF, T-suppressor factor, antigen-specific unless otherwise stated; Ts alI, TsF-alI, T-suppressor cells and factors alIerent, which only act when given early in the immune response. They differ from Ts-ind by not acting through the Ts-effjT-acc circuit; Ts eff, TsF-eff, antigen-directed Ts and TsF effector which act at the effector stage of the immune response; Ts-ind, TsF-ind, Ts and TsF inducer that induce idiotype-directed Ts-trans and antigen-directed Ts-eff; Ts-trans, TsF-trans, Ts and TsF are anti-idiotypic and act on the Ts-eff. 37 0732-0582/86/0410-0037$02.00 ASHERSON, COLIZZI & ZEMBALA such as antibody, which augments and depresses immune responses and has modes of action through the mast cell
Annual Review of Immunology – Annual Reviews
Published: Apr 1, 1986
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