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Antimicrobial Chemotherapy

Antimicrobial Chemotherapy By ERNEST J AWETZ Departments of Microbiology, Medicine, and Pediatrics, University of California School of Medicine, San Francisco, California Antibiotics have been employed in clinical medicine for almost a decade and a half-yet the field of antimicrobial therapy is not in a stable state. The literature dealing with chemotherapeutic agents and their use is grow­ ing at an unprecedented rate. Thus, a drug like erythromycin (of some use­ fulness but not of revolutionary importance), which was announced in 1952 (1), could boast over 420 titles in "its" bibliography by 1955! To cope with this flood of printed matter there have appeared many reviews, and reviews of reviews. The present summary fits into the latter category. The extensive and superbly analytical review of antibiotics by Eagle & Saz in the Annual Review of Microbiology, 1955 (2), so thoroughly covered all fundamental aspects of the field that little new m aterial can be added at this time. During 1955 there have been no striking advances in the under­ standing of antibiotic action, and no new drugs of established importance have been discovered. Among the dozens of antibiotics announced during the past year, a few have had striking names; but their http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Microbiology Annual Reviews

Antimicrobial Chemotherapy

Jawetz, E
Annual Review of Microbiology , Volume 10 (1) – Oct 1, 1956
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Publisher
Annual Reviews
Copyright
Copyright 1956 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0066-4227
eISSN
1545-3251
DOI
10.1146/annurev.mi.10.100156.000505
pmid
13363356
Publisher site
See Article on Publisher Site

Abstract

By ERNEST J AWETZ Departments of Microbiology, Medicine, and Pediatrics, University of California School of Medicine, San Francisco, California Antibiotics have been employed in clinical medicine for almost a decade and a half-yet the field of antimicrobial therapy is not in a stable state. The literature dealing with chemotherapeutic agents and their use is grow­ ing at an unprecedented rate. Thus, a drug like erythromycin (of some use­ fulness but not of revolutionary importance), which was announced in 1952 (1), could boast over 420 titles in "its" bibliography by 1955! To cope with this flood of printed matter there have appeared many reviews, and reviews of reviews. The present summary fits into the latter category. The extensive and superbly analytical review of antibiotics by Eagle & Saz in the Annual Review of Microbiology, 1955 (2), so thoroughly covered all fundamental aspects of the field that little new m aterial can be added at this time. During 1955 there have been no striking advances in the under­ standing of antibiotic action, and no new drugs of established importance have been discovered. Among the dozens of antibiotics announced during the past year, a few have had striking names; but their

Journal

Annual Review of Microbiology – Annual Reviews

Published: Oct 1, 1956

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