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of asbes tos, shortly after the tum of the century, the ftrst case of lung ftbrosis, later called asbestosis, was recognized and reported to the British government. By the 1930s, asbestosis risk was clearly recognized in asbestos textile man ufacturing. This risk was shown to be dose-related in a US Public Health Service study in the late 1930s (1 1 ), leading to the first suggestion of a dust level putatively associated with no risk of disease (threshold limit value, TLV).l Asbestosis risk in users of asbestos products was regarded as minimal as a result of a 1946 report on New England shipyard workers (19). However, 20 years later, studies of insulators showed substantial risk of lung fibrosis (46). Case reports in the 1930s first suggested that an increased number of lung cancers seemed to occur in workers with asbestosis. An autopsy study in the UK supporting this association was published in the late 1940s (32) and, in 1955, the first epidemiologic study of workers in asbestos manufacturing con vincingly showed an increased lung cancer risk (10). In 1967, a study of US asbestos products manufacturing workers showed this risk to be dose related ( 12). Excess lung
Annual Review of Public Health – Annual Reviews
Published: May 1, 1986
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