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CH Isotype 'Switching' During Normal B-Lymphocyte Development

CH Isotype 'Switching' During Normal B-Lymphocyte Development This discussion focuses on whether any relationships exist between the patterns of murine B-Iymphocyte responses to different sets of stimuli and their poten­ tial for expression of Igl heavy-chain isotypes. We also attempt to treat the I Abbreviations used in this paper: Ab, antibody; ABC, antigen-binding cell; Ag, antigen; A­ MuLV, Abelson murine leukemia virus; ASC, Ascaris suum; BA, Brucella abortus; BL, bacterial levan; BM, bone marrow; BUdR, 5' -bromodeoxyuridine; CH, constant region of heavy chain; ConA, concanavalin A; Oex. dextran; ONP dinitrophenyl; FACS. fluorescence-activated cell . sorter; FCS. felal calf serum; FcR". Fe receptor for IgA; FITC. fluorescein isothiocyanate; FL. fluorescein; Ga!. galactose; GlcNAc-GG. N-acetylglucosaminyl-coupled goat IgG; H-LPS. hap­ tenated lipopolysaccharide: HRBC, horse red blood cells; Hy. Limulus polyphemus hemocyanin; i.g .. intragastric: Ig . immunoglobulin: IL-2. interleukin 2; In. inulin; i.p.. intraperitoneal: i.v.. intravenous: 111, 1 sequence of heavy chain: LPS. lipopolysaccharide; 2-ME. 2-mercaptoethanol: gellin: PP. Peyer's patches: PPO. purified protein derivative of tuberculin: PW-LPS. phenol/water cyanate: SII' switch sequence of heavy chain: sIg. surface immunoglobulin: SPA. Staphylococcal extracted lipopolysaccharide: TH. helper T cell: T He"g)' antigen-specific helper T cell: TI. thymus­ independent: TO. thymus-dependent: TNP. Irinitrophenyl: Tx. thymectomized: TXO. cholera toxoid: TXN. cholera toxin: VH' http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Immunology Annual Reviews

CH Isotype 'Switching' During Normal B-Lymphocyte Development

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Publisher
Annual Reviews
Copyright
Copyright 1984 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0732-0582
eISSN
1545-3278
DOI
10.1146/annurev.iy.02.040184.002425
pmid
6085751
Publisher site
See Article on Publisher Site

Abstract

This discussion focuses on whether any relationships exist between the patterns of murine B-Iymphocyte responses to different sets of stimuli and their poten­ tial for expression of Igl heavy-chain isotypes. We also attempt to treat the I Abbreviations used in this paper: Ab, antibody; ABC, antigen-binding cell; Ag, antigen; A­ MuLV, Abelson murine leukemia virus; ASC, Ascaris suum; BA, Brucella abortus; BL, bacterial levan; BM, bone marrow; BUdR, 5' -bromodeoxyuridine; CH, constant region of heavy chain; ConA, concanavalin A; Oex. dextran; ONP dinitrophenyl; FACS. fluorescence-activated cell . sorter; FCS. felal calf serum; FcR". Fe receptor for IgA; FITC. fluorescein isothiocyanate; FL. fluorescein; Ga!. galactose; GlcNAc-GG. N-acetylglucosaminyl-coupled goat IgG; H-LPS. hap­ tenated lipopolysaccharide: HRBC, horse red blood cells; Hy. Limulus polyphemus hemocyanin; i.g .. intragastric: Ig . immunoglobulin: IL-2. interleukin 2; In. inulin; i.p.. intraperitoneal: i.v.. intravenous: 111, 1 sequence of heavy chain: LPS. lipopolysaccharide; 2-ME. 2-mercaptoethanol: gellin: PP. Peyer's patches: PPO. purified protein derivative of tuberculin: PW-LPS. phenol/water cyanate: SII' switch sequence of heavy chain: sIg. surface immunoglobulin: SPA. Staphylococcal extracted lipopolysaccharide: TH. helper T cell: T He"g)' antigen-specific helper T cell: TI. thymus­ independent: TO. thymus-dependent: TNP. Irinitrophenyl: Tx. thymectomized: TXO. cholera toxoid: TXN. cholera toxin: VH'

Journal

Annual Review of Immunology – Annual Reviews

Published: Apr 1, 1984

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