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/lp/annual-reviews/industrial-food-animal-production-antimicrobial-resistance-and-human-7RN1D7Wqwy
- Publisher
- Annual Reviews
- Copyright
- Copyright © 2008 by Annual Reviews. All rights reserved
- ISSN
- 0163-7525
- eISSN
- 1545-2093
- DOI
- 10.1146/annurev.publhealth.29.020907.090904
- pmid
- 18348709
- Publisher site
- See Article on Publisher Site
Abstract
Antimicrobial resistance is a major public health crisis, eroding the discovery of antimicrobials and their application to clinical medicine. There is a general lack of knowledge of the importance of agricultural antimicrobial use as a factor in antimicrobial resistance even among experts in medicine and public health. This review focuses on agricultural antimicrobial drug use as a major driver of antimicrobial resistance worldwide for four reasons: It is the largest use of antimicrobials worldwide; much of the use of antimicrobials in agriculture results in subtherapeutic exposures of bacteria; drugs of every important clinical class are utilized in agriculture; and human populations are exposed to antimicrobial-resistant pathogens via consumption of animal products as well as through widespread release into the environment.
Journal
Annual Review of Public Health – Annual Reviews
Published: Apr 21, 2008