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Some Aspects of Central Nervous Pharmacology

Some Aspects of Central Nervous Pharmacology The literature on central nervous effects of drugs continues to grow ex­ ponentially. For the year 1961, Psychopharmacology A bstracts alone shows more than 3,000 titles, and several hundred of these may be classified as reviews. It would be impossible to digest all the literature pertinent to the present annual review or even to list the titles within the available space. Instead, we shall have to be satisfied with a representative sample sufficient to serve as a basis for discussion of some current trends. The samples selected will not necessarily be the best work in the field, and the valuable contribu­ tions of many authors will be neglected, also some potentially reviewable fields will receive scant or no mention. For this spotty treatment we will offer no excuse except our limitations of time, space, inclination, and competence to do justice to this broad and important field of research. THEORETICAL CONSIDERATIONS ON DRUG ACTIONS UPON CENTRAL NEURONES AND SYNAPSES Classes of junctional transmission.-It is an aphorism that drug actions involving neurones or effectors occur primarily at synaptic regions rather than upon the unapposed membranes of cells. Drugs have served as valuable tools in unscrambling the complexities of synaptic interactions http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Pharmacology and Toxicology Annual Reviews

Some Aspects of Central Nervous Pharmacology

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Publisher
Annual Reviews
Copyright
Copyright 1963 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0362-1642
eISSN
1545-4304
DOI
10.1146/annurev.pa.03.040163.001101
Publisher site
See Article on Publisher Site

Abstract

The literature on central nervous effects of drugs continues to grow ex­ ponentially. For the year 1961, Psychopharmacology A bstracts alone shows more than 3,000 titles, and several hundred of these may be classified as reviews. It would be impossible to digest all the literature pertinent to the present annual review or even to list the titles within the available space. Instead, we shall have to be satisfied with a representative sample sufficient to serve as a basis for discussion of some current trends. The samples selected will not necessarily be the best work in the field, and the valuable contribu­ tions of many authors will be neglected, also some potentially reviewable fields will receive scant or no mention. For this spotty treatment we will offer no excuse except our limitations of time, space, inclination, and competence to do justice to this broad and important field of research. THEORETICAL CONSIDERATIONS ON DRUG ACTIONS UPON CENTRAL NEURONES AND SYNAPSES Classes of junctional transmission.-It is an aphorism that drug actions involving neurones or effectors occur primarily at synaptic regions rather than upon the unapposed membranes of cells. Drugs have served as valuable tools in unscrambling the complexities of synaptic interactions

Journal

Annual Review of Pharmacology and Toxicology – Annual Reviews

Published: Apr 1, 1963

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