Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/annual-reviews/the-cd40-antigen-and-its-ligand-XnCjPGbmlh
References (134)
-
J. Grimaldi, Raul Torres, C. Kozak, R. Chang, Edward Clark, Maureen Howard, D. Cockayne (1992)
Genomic structure and chromosomal mapping of the murine CD40 gene.Journal of immunology, 149 12
-
A. Galy, H. Spits (1992)
CD40 is functionally expressed on human thymic epithelial cells.Journal of immunology, 149 3
-
P. Björck, C. Elenström-Magnusson, A. Rosén, E. Severinson, S. Paulie (1993)
CD23 and CD21 function as adhesion molecules in homotypic aggregation of human B lymphocytesEuropean Journal of Immunology, 23
-
S. Saeland, rie Duver, I. Moreau, J. Banchereau (1993)
Human B cell precursors proliferate and express CD23 after CD40 ligationThe Journal of Experimental Medicine, 178
-
M. Peitsch, C. Jongeneel (1993)
A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors.International immunology, 5 2
-
N. McDonald, W. Hendrickson (1993)
A structural superfamily of growth factors containing a cystine knot motifCell, 73
-
David Gray, M. Kosco, B. Stockinger (1991)
Novel pathways of antigen presentation for the maintenance of memory.International immunology, 3 2
-
J. Banchereau (1993)
Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10The Journal of Experimental Medicine, 177
-
N. Renard, V. Duvert, D. Blanchard, J. Banchereau, S. Saeland (1994)
Activated CD4+ T cells induce CD40-dependent proliferation of human B cell precursors.Journal of immunology, 152 4
-
D. Blanchard, Claude Gaillard, P. Hermann, J. Banchereau (1994)
Role of CD40 antigen and interleukin‐2 in T cell‐dependent human B lymphocyte growthEuropean Journal of Immunology, 24
-
H. Dürkop, U. Latza, Michael Hummel, F. Eitelbach, Brian Seed, Harald Stein (1992)
Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's diseaseCell, 68
-
J. Banchereau, P. Paoli, A. Vallé, Eric Garcia, Françoise Rousset (1991)
Long-term human B cell lines dependent on interleukin-4 and antibody to CD40.Science, 251 4989
-
J. Gauchat, J. Aubry, G. Mazzei, P. Life, T. Jomotte, G. Elson, J. Bonnefoy (1993)
Human CD40‐ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE productionFEBS Letters, 315
-
T. Foy, D. Shepherd, F. Durie, A. Aruffo, J. Ledbetter, R. Noelle (1993)
In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39The Journal of Experimental Medicine, 178
-
G. Chelvanayagam, J. Heringa, P. Argos (1992)
Anatomy and evolution of proteins displaying the viral capsid jellyroll topology.Journal of molecular biology, 228 1
-
FranyoisePorteuand Nathan (1990)
Shedding of tumor necrosis factor receptors by activated human neutrophilsThe Journal of Experimental Medicine, 172
-
C. Caux, C. Dezutter‐Dambuyant, Daniel Schmitt, J. Banchereau (1992)
GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cellsNature, 360
-
Brief Definitive Report TRANSFORMING GROWTH FACTOR # SPECIFICALLY ENHANCES IgA PRODUCTION BY LIPOPOLYSACCHARIDE-STIMULATED -
R. Goodwin, W. Din, T. Davis‐Smith, Dirk Anderson, S. Gimpel, Timothy Sato, C. Maliszewski, C. Brannan, N. Copeland, N. Jenkins, T. Farrah, R. Armitage, W. Fanslow, Craig Smith (1993)
Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factorEuropean Journal of Immunology, 23
-
D. Macchia, F. Almerigogna, P. Parronchi, A. Ravina, E. Maggi, S. Romagnani (1993)
Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cellsNature, 363
-
B. Castle, K. Kishimoto, C. Stearns, M. Brown, M. Kehry (1993)
Regulation of expression of the ligand for CD40 on T helper lymphocytes.Journal of immunology, 151 4
-
N. Itoh, S. Nagata (1993)
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen.The Journal of biological chemistry, 268 15
-
P. Lane, A. Traunecker, S. Hubele, S. Inui, A. Lanzavecchia, D. Gray (1992)
Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytesEuropean Journal of Immunology, 22
-
F. Kroese, W. Timens, P. Nieuwenhuis (1990)
Germinal center reaction and B lymphocytes: morphology and function.Current topics in pathology. Ergebnisse der Pathologie, 84 ( Pt 1)
-
T. Barrett, G. Shu, E. Clark (1991)
CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells.Journal of immunology, 146 6
-
François Bontems, Christian Roumestand, B. Gilquin, André Ménez, Flavio Toma (1991)
Refined structure of charybdotoxin: common motifs in scorpion toxins and insect defensins.Science, 254 5037
-
E. Jones, D. Stuart, N. Walker (1989)
Structure of tumour necrosis factorNature, 338
-
N. Ramesh, V. Ramesh, J. Gusella, R. Geha (1993)
Chromosomal localization of the gene for human B-cell antigen CD40Somatic Cell and Molecular Genetics, 19
-
W. Fanslow, D. Anderson, K. Grabstein, E. Clark, D. Cosman, R. Armitage (1992)
Soluble forms of CD40 inhibit biologic responses of human B cells.Journal of immunology, 149 2
-
C. Kooten, Claude Gaillard, J. Galizzi, P. Hermann, F. Fossiez, J. Banchereau, D. Blanchard (1994)
B cells regulate expression of CD40 ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40European Journal of Immunology, 24
-
L. Tartaglia, D. Goeddel (1992)
Two TNF receptors.Immunology today, 13 5
-
Yong‐jun Liu, D. Mason, G. Johnson, Sandra Abbot, C. Gregory, D. Hardie, J. Gordon, I. Maclennan (1991)
Germinal center cells express bcl‐2 protein after activation by signals which prevent their entry into apoptosisEuropean Journal of Immunology, 21
-
P. Björck, B. Axelsson, S. Paulie (1991)
Expression of CD40 and CD43 during Activation of Human B LymphocytesScandinavian Journal of Immunology, 33
-
H. Engelmann, H. Holtmann, C. Brakebusch, Y. Avni, I. Sarov, Y. Nophar, E. Hadas, O. Leitner, D. Wallach (1990)
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.The Journal of biological chemistry, 265 24
-
J. Gauchat, S. Henchoz, G. Mazzei, J. Aubry, T. Brunner, H. Blasey, P. Life, D. Talabot, L. Flores-Romo, Jeff Thompson, K. Kishi, J. Butterfield, C. Dahinden, J. Bonnefoy (1993)
Induction of human IgE synthesis in B cells by mast cells and basophilsNature, 365
-
S. Inui, T. Kaisho, H. Kikutani, I. Stamenkovic, B. Seed, E. Clark, T. Kishimoto (1990)
Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40European Journal of Immunology, 20
-
C. Riedel, T. Owens, G. Nossal (1988)
A significant proportion of normal resting B cells are induced to secrete immunoglobulin through contact with anti‐receptor antibody‐activated helper T cells in clonal culturesEuropean Journal of Immunology, 18
-
A. Brian (1988)
Stimulation of B-cell proliferation by membrane-associated molecules from activated T cells.Proceedings of the National Academy of Sciences of the United States of America, 85 2
-
C. Ibáñez, T. Ebendal, G. Barbany, J. Murray-Rust, T. Blundell, H. Persson (1992)
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene productCell, 69
-
A. Durandy, C. Schiff, J. Bonnefoy, M. Forveille, F. Rousset, G. Mazzei, M. Milili, Alain Fischer (1993)
Induction by anti‐CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X‐linked hyper IgM syndromeEuropean Journal of Immunology, 23
-
J. Disanto, J. Bonnefoy, J. Gauchat, A. Fischer, G. Basile (1993)
CD40 ligand mutations in X-linked immunodeficiency with hyper-IgMNature, 361
-
J. Yamagishi, H. Kawashima, N. Matsuo, M. Ohue, M. Yamayoshi, T. Fukui, H. Kotani, R. Furuta, K. Nakano, M. Yamada (1990)
Mutational analysis of structure--activity relationships in human tumor necrosis factor-alpha.Protein engineering, 3 8
-
S. Rabizadeh, Justin Oh, Li-Tao Zhong, Jie Yang, C. Bitler, L. Butcher, D. Bredesen (1993)
Induction of apoptosis by the low-affinity NGF receptor.Science, 261 5119
-
Yong‐jun Liu, D. Joshua, Gwyn Williams, Christopher Smith, J. Gordon, I. Maclennan (1989)
Mechanism of antigen-driven selection in germinal centresNature, 342
-
W. Loenen, L. Gravestein, S. Beumer, C. Melief, A. Hagemeijer, J. Borst (1992)
Genomic organization and chromosomal localization of the human CD27 gene.Journal of immunology, 149 12
-
J. Gordon, M. Millsum, G. Guy, J. Ledbetter (1987)
Synergistic interaction between interleukin 4 and anti‐Bp50 (CDw40) revealed in a novel B cell restimulation assayEuropean Journal of Immunology, 17
-
J. Jacob, G. Kelsoe, K. Rajewsky, U. Weiss (1991)
Intraclonal generation of antibody mutants in germinal centresNature, 354
-
Peter DiStefano, Eugene Johnson (1988)
Identification of a truncated form of the nerve growth factor receptor.Proceedings of the National Academy of Sciences of the United States of America, 85 1
-
R. Allen, R. Armitage, M. Conley, H. Rosenblatt, N. Jenkins, N. Copeland, M. Bedell, S. Edelhoff, C. Disteche, Denise Simoneaux, W. Fanslow, J. Belmont, M. Spriggs (1993)
CD40 ligand gene defects responsible for X-linked hyper-IgM syndromeScience, 259
-
X. Ostade, P. Vandenabeele, B. Everaerdt, H. Loetscher, R. Gentz, M. Brockhaus, W. Lesslauer, J. Tavernier, P. Brouckaert, W. Fiers (1993)
Human TNF mutants with selective activity on the p55 receptorNature, 361
-
L. Terstappen, Shiang Huang, M. Safford, P. Lansdorp, Loken (1991)
Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells.Blood, 77 6
-
T. Owens (1988)
A noncognate interaction with anti‐receptor antibody‐activated helper T cells induces small resting murine B cells to proliferate and to secrete antibodyEuropean Journal of Immunology, 18
-
Craig Smith, T. Davis, J. Wignall, W. Din, Theresa Farrah, C. Upton, G. McFadden, R. Goodwin (1991)
T2 open reading frame from the Shope fibroma virus encodes a soluble form of the TNF receptor.Biochemical and biophysical research communications, 176 1
-
Peter Lane, Thomas Brocker, S. Hubele, Elizabetta Padovan, Antonio Lanzavecchia, Fiona McConnell (1993)
Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activationThe Journal of Experimental Medicine, 177
-
P. Krammer, K. Debatin (1992)
When apoptosis failsCurrent Biology, 2
-
X. Zhang, I. Weber, M. Chen (1992)
Site-directed mutational analysis of human tumor necrosis factor-alpha receptor binding site and structure-functional relationship.The Journal of biological chemistry, 267 33
-
M. Roy, T. Waldschmidt, A. Aruffo, J. Ledbetter, R. Noelle (1993)
The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.Journal of immunology, 151 5
-
David Camerini, Gerd Walz, W. Loenen, Jannie Borst, Brian Seed (1991)
The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.Journal of immunology, 147 9
-
F. Kroese, A. Wubbena, H. Seijen, P. Nieuwenhuis (1987)
Germinal centers develop oligoclonallyEuropean Journal of Immunology, 17
-
M. Alderson, R. Armitage, T. Tough, L. Strockbine, W. Fanslow, Melanie Spriggsr (1993)
CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40The Journal of Experimental Medicine, 178
-
Rie Watanabe‐Fukunaga, C. Brannan, N. Copeland, N. Jenkins, S. Nagata (1992)
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosisNature, 356
-
U. Mayer, R. Nischt, E. Poschl, K. Mann, K. Fukuda, Martin Geri, Yoshihiko Yamada, R. Timpl (1993)
A single EGF‐like motif of laminin is responsible for high affinity nidogen binding.The EMBO Journal, 12
-
M. Bajaj, M. Waterfield, J. Schlessinger, W. Taylor, T. Blundell (1987)
On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.Biochimica et biophysica acta, 916 2
-
T. Schall, Martyn Lewis, K. Koller, Angela Lee, G. Rice, G. Wong, T. Gatanaga, G. Granger, R. Lentz, H. Raab, W. Kohr, D. Goeddel (1990)
Molecular cloning and expression of a receptor for human tumor necrosis factorCell, 61
-
Seth Lederman, Michael Yellin, Alexander Krichevsky, John Belko, Julie Lee, L. Chess (1992)
Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)The Journal of Experimental Medicine, 175
-
Y. Kim, K. Pollok, Z. Zhou, A. Shaw, J. Bohlen, M. Fraser, B. Kwon (1993)
Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56lck1.Journal of immunology, 151 3
-
H. Loetscher, Y. Pan, H. Lahm, R. Gentz, M. Brockhaus, H. Tabuchi, W. Lesslauer (1990)
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptorCell, 61
-
M. Chao (1992)
Neurotrophin receptors: A window into neuronal differentiationNeuron, 9
-
B. Witthuhn, F. Quelle, O. Silvennoinen, T. Yi, Bo Tang, O. Miura, J. Ihle (1993)
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietinCell, 74
-
D. Parker (1993)
T cell-dependent B cell activation.Annual review of immunology, 11
-
C. Law, B. Wörmann, T. Lebien (1990)
Analysis of expression and function of CD40 on normal and leukemic human B cell precursors.Leukemia, 4 11
-
F. Rousset, Eric García, J. Banchereau (1991)
Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigenThe Journal of Experimental Medicine, 173
-
Yuji Kobayashi, H. Takashima, H. Tamaoki, Y. Kyōgoku, P. Lambert, H. Kuroda, N. Chino, Takushi Watanabe, Terutoshi Kimura, S. Sakakibara, L. Moroder (1991)
The cystine‐stabilized α‐helix: A common structural motif of ion‐channel blocking neurotoxic peptidesBiopolymers, 31
-
T. Farrah, C. Smith (1992)
Emerging cytokine familyNature, 358
-
J. Tew, M. Kosco, G. Burton, A. Szakal (1990)
Follicular Dendritic Cells as Accessory CellsImmunological Reviews, 117
-
N. Ramesh, R. Fuleihan, Vijay Ramesh, Seth Lederman, Michael Yellin, Sunita Sharma, Leonard Chess, Fred Rosen, R. Geha (1993)
Deletions in the ligand for CD40 in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1).International immunology, 5 7
-
E. Jones, D. Stuart, N. Walker (1992)
Crystal structure of TNF.Immunology series, 56
-
M. Adachi, Rie Watanabe‐Fukunaga, S. Nagata (1993)
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice.Proceedings of the National Academy of Sciences of the United States of America, 90
-
Andrey Shaw, '. Chalupny, J. Whitney, Craig Hammond, Kurt Amrein, Paula Kavathas, B. Sefton, K. John, '. Rose (1990)
Short related sequences in the cytoplasmic domains of CD4 and CD8 mediate binding to the amino-terminal domain of the p56lck tyrosine protein kinaseMolecular and Cellular Biology, 10
-
Sten Braesch-Andersen, Staffan Paulie, H. Koho, H. Nika, P. Aspenström, P. Perlmann (1989)
Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.Journal of immunology, 142 2
-
A. Butch, G. Chung, J. Hoffmann, M. Nahm (1993)
Cytokine expression by germinal center cells.Journal of immunology, 150 1
-
P. Valent, O. Majdic, D. Maurer, M. Bodger, M. Muhm, P. Bettelheim (1990)
Further characterization of surface membrane structures expressed on human basophils and mast cells.International archives of allergy and applied immunology, 91 2
-
R. Hintzen, R. Jong, C. Hack, M. Chamuleau, E. Vries, I. Berge, J. Borst, R. Lier (1991)
A soluble form of the human T cell differentiation antigen CD27 is released after triggering of the TCR/CD3 complex.Journal of immunology, 147 1
-
M. Holder, Hong Wang, A. Milner, Monserat Casamayor, R. Armitage, M. Spriggs, W. Fanslow, I. Maclennan, C. Gregory, J. Gordon (1993)
Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl‐2 inductionEuropean Journal of Immunology, 23
-
J. Punnonen, G. Aversa, B. Cocks, Andrew Mckenzie, Satish Menon, G. Zurawski, R. Malefyt, J. Vries (1993)
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Proceedings of the National Academy of Sciences of the United States of America, 90
-
E. Clark, K. Grabstein, G. Shu (1992)
Cultured human follicular dendritic cells. Growth characteristics and interactions with B lymphocytes.Journal of immunology, 148 11
-
N. Itoh, S. Yonehara, A. Ishii, M. Yonehara, S. Mizushima, M. Sameshima, A. Hase, Y. Seto, S. Nagata (1991)
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosisCell, 66
-
S. Mallett, A. Barclay (1991)
A new superfamily of cell surface proteins related to the nerve growth factor receptor.Immunology today, 12 7
-
J. Gauchat, G. Aversa, H. Gascan, J. Vries (1992)
Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE productionInternational Immunology, 4
-
W. Loenen, E. Vries, L. Gravestein, R. Hintzen, R. Lier, J. Borst (1992)
The CD27 membrane receptor, a lymphocyte‐specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosisEuropean Journal of Immunology, 22
-
J. Pène, F. Rousset, F. Brière, I. Chrétien, J. Bonnefoy, H. Spits, T. Yokota, N. Arai, K. Arai, J. Banchereau (1988)
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.Proceedings of the National Academy of Sciences of the United States of America, 85 18
-
L. Tartaglia, M. Rothe, Yan Hu, D. Goeddel (1993)
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptorCell, 73
-
R. Goodwin, M. Alderson, Craig Smith, R. Armitage, T. Vandenbos, R. Jerzy, T. Tough, M. Schoenborn, T. Davis‐Smith, Kathryn Hennen, B. Falk, D. Cosman, E. Baker, G. Sutherland, K. Grabstein, T. Farrah, J. Giri, M. Beckmann (1993)
Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factorCell, 73
-
P. Cohen, R. Eisenberg (1992)
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.Immunology today, 13 11
-
Craig Smith, T. Davis, D. Anderson, L. Solam, MP Beckmann, R. Jerzy, S. Dower, D. Cosman, R. Goodwin (1990)
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins.Science, 248 4958
-
G. Kansas, Gary Wood, Thomas Tedder (1991)
Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes.Journal of immunology, 146 7
-
Yong‐jun Liu, G. Johnson, J. Gordon, I. Maclennan (1992)
Germinal centres in T-cell-dependent antibody responses.Immunology today, 13 1
-
I. Moreau, V. Duvert, J. Banchereau, S. Saeland (1993)
Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells.Blood, 81 5
-
M. Conley (1992)
Molecular approaches to analysis of X-linked immunodeficiencies.Annual review of immunology, 10
-
D. Graf, U. Korthäuer, H. Mages, G. Senger, R. Kroczek (1992)
Cloning of TRAP, a ligand for CD40 on human T cellsEuropean Journal of Immunology, 22
-
D. Hollenbaugh, L. Grosmaire, C. Kullas, N. Chalupny, S. Braesch-Andersen, Randolph NoelIe, Ivan, '. Stamenkovic, J. Ledbetter, A. Aruffo (1992)
The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co‐stimulatory activity.The EMBO Journal, 11
-
M. Jumper, J. Splawski, P. Lipsky, K. Meek (1994)
Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells.Journal of immunology, 152 2
-
Craig Smith, H. Gruss, T. Davis, Dirk Anderson, T. Farrah, E. Baker, G. Sutherland, C. Brannan, N. Copeland, N. Jenkins, K. Grabstein, B. Gliniak, Ian McAlister, W. Fanslow, M. Alderson, B. Falk, S. Gimpel, S. Gillis, W. Din, R. Goodwin, R. Armitage (1993)
CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNFCell, 73
-
R. Armitage, T. Tough, B. Macduff, W. Fanslow, M. Spriggs, F. Ramsdell, M. Alderson (1993)
CD40 ligand is a T cell growth factorEuropean Journal of Immunology, 23
-
B. Kwon, S. Weissman (1989)
cDNA sequences of two inducible T-cell genes.Proceedings of the National Academy of Sciences of the United States of America, 86 6
-
G. Aversa, J. Punnonen, J. Vries (1993)
The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activationThe Journal of Experimental Medicine, 177
-
R. Armitage, W. Fanslow, L. Strockbine, Timothy Sato, K. Clifford, B. Macduff, Dirk Anderson, S. Gimpel, T. Davis‐Smith, C. Maliszewski, E. Clark, Craig Smith, K. Grabstein, D. Cosman, M. Spriggs (1992)
Molecular and biological characterization of a murine ligand for CD40Nature, 357
-
S. Shchelkunov, V. Blinov, L. Sandakhchiev (1993)
Genes of variola and vaccinia viruses necessary to overcome the host protective mechanismsFEBS Letters, 319
-
S. Sprang (1990)
The divergent receptors for TNF.Trends in biochemical sciences, 15 10
-
S. Paulie, A. Rosén, B. Ehlin‐Henriksson, S. Braesch-Andersen, E. Jakobson, H. Koho, P. Perlmann (1989)
The human B lymphocyte and carcinoma antigen, CDw40, is a phosphoprotein involved in growth signal transduction.Journal of immunology, 142 2
-
R. Noelle, E. Snow (1990)
Cognate interactions between helper T cells and B cells.Immunology today, 11 10
-
Seth Lederman, M. Yellin, Giorgio Inghirami, Jj Lee, Dm Knowles, Leonard Chess (1992)
Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help.Journal of immunology, 149 12
-
F. Uckun, K. Gajl-Peczalska, D. Myers, W. Jaszcz, S. Haissig, J. Ledbetter (1990)
Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells.Blood, 76 12
-
C. Berek, A. Berger, M. Apel (1991)
Maturation of the immune response in germinal centersCell, 67
-
A. Oehm, Iris Behrmann, W. Falk, M. Pawlita, Gerhard Maier, C. Klas, M. Li‐Weber, S. Richards, J. Dhein, B. Trauth (1992)
Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.The Journal of biological chemistry, 267 15
-
S. Raffioni, Ralph Bradshaw, Stephen Buxser (1993)
The receptors for nerve growth factor and other neurotrophins.Annual review of biochemistry, 62
-
T. Mustelin, P. Burn (1993)
Regulation of src family tyrosine kinases in lymphocytes.Trends in biochemical sciences, 18 6
-
J. Aubry, S. Pochon, P. Graber, K. Jansen, J. Bonnefoy (1992)
CD21 is a ligand for CD23 and regulates IgE productionNature, 358
-
Susan Howard, Susan Howard, Y. Chan, Geoffrey Smith, Geoffrey Smith (1991)
Vaccinia virus homologues of the Shope fibroma virus inverted terminal repeat proteins and a discontinuous ORF related to the tumor necrosis factor receptor family.Virology, 180 2
-
A. Vallé, C. Zuber, T. Defrance, O. Djossou, Menno Riem, J. Banchereau (1989)
Activation of human B lymphocytes through CD40 and interleukin 4European Journal of Immunology, 19
-
X. Ostade, J. Tavernier, T. Prangé, W. Fiers (1991)
Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis.The EMBO Journal, 10
-
J. Schlessinger, A. Ullrich (1992)
Growth factor signaling by receptor tyrosine kinasesNeuron, 9
-
A.F.J.M. Ackerveken, J. Kan, M. Joosten, J. Muisers, H. Verbakel, P. Wit (1993)
Characterization of two putative pathogenicity genes of the fungal tomato pathogen Cladosporium fulvum.Molecular plant-microbe interactions : MPMI, 6 2
-
Masaaki Murakami, M. Narazaki, Masahiko Hibi, H. Yawata, K. Yasukawa, Michinari Hamaguchi, Tetsuya Taga, Tadamitsu Kishimoto (1991)
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.Proceedings of the National Academy of Sciences of the United States of America, 88 24
-
M. Baens, M. Chaffanet, J. Cassiman, H. Berghe, P. Marynen (1993)
Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid.Genomics, 16 1
-
F. Hu, D. Pickup (1991)
Transcription of the terminal loop region of vaccinia virus DNA is initiated from the telomere sequences directing DNA resolution.Virology, 181 2
-
F. Durie, R. Fava, T. Foy, A. Aruffo, J. Ledbetter, R. Noelle (1993)
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.Science, 261 5126
-
C. Ren, Tomohiro Morio, Shu Fu, R. Geha (1994)
Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2The Journal of Experimental Medicine, 179
-
S. Mallett, S. Fossum, A. Barclay (1990)
Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes‐‐a molecule related to nerve growth factor receptor.The EMBO Journal, 9
-
Hugues, Gascan, Jean-Frangois Gauchat, Marie-Grazia Roncarolo, Hans, Yssel, Hergen, Spits, Jan, De Vries (1991)
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clonesThe Journal of Experimental Medicine, 173
-
I. Maclennan, D. Gray (1986)
Antigen‐Driven Selection of Virgin and Memory B CellsImmunological Reviews, 91
-
M. Androlewicz, J. Browning, C. Ware (1992)
Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma.The Journal of biological chemistry, 267 4
-
A. Aruffo, M. Farrington, D. Hollenbaugh, Xu Li, A. Milatovich, S. Nonoyama, J. Bajorath, L. Grosmaire, R. Stenkamp, M. Neubauer, R. Roberts, R. Noelle, J. Ledbetter, U. Francke, H. Ochs (1993)
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndromeCell, 72
-
H. Jabara, S. Fu, R. Geha, D. Vercelli (1990)
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cellsThe Journal of Experimental Medicine, 172
- Publisher
- Annual Reviews
- Copyright
- Copyright 1994 Annual Reviews. All rights reserved
- Subject
- Review Articles
- ISSN
- 0732-0582
- eISSN
- 1545-3278
- DOI
- 10.1146/annurev.iy.12.040194.004313
- pmid
- 7516669
- Publisher site
- See Article on Publisher Site
Abstract
CD40 is an integral membrane protein found on the surface of B lym phocytes, dendritic cells, follicular dendritic cells, hematopoietic pro genitor cells, epithelial cells, and carcinomas. It is a 45-50 kDa glycoprotein of 277 aa, which is a member of the tumor necrosis factor receptor super family. The CD40 gene maps to h uman chromosome 20q 1 1 -2-q1 3-2. CD40 binds to a ligand (CD40-L) which is an 35 kDa glycoprotein of 261 aa, a member of the tumor necrosis factor s uperfamily. The CD40-L gene maps to h uman chromosome Xq24. This CD40-L is expressed on activated T cells, mostly CD4 + but also some CD8 + as well as basophils/mast cells. The CD40-L is defective in the X-linked hyper- IgM syndrome. Cross-linking of CD40 with immobilized anti-CD40 or cells expressing CD40-L induces B cells to proliferate strongly, and addition of I L-4 or IL-1 3 allows the generation of factor-dependent long-term normal h uman B cell lines and the secretion of IgE following isotype switching. Addition of IL- l O results in very high immunoglobulin production with limited cell proliferation. IL- I O induces naive B cells to produce IgG3, IgGI, and IgA l
Journal
Annual Review of Immunology – Annual Reviews
Published: Apr 1, 1994