Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/annual-reviews/the-molecular-cell-biology-of-interferon-gamma-and-its-receptor-UzToZWzuRs
References (93)
-
S. Hemmi, G. Merlin, M. Aguet (1992)
Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer.Proceedings of the National Academy of Sciences of the United States of America, 89 7
-
G. Bancroft, R. Schreiber, E. Unanue (1991)
Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid MouseImmunological Reviews, 124
-
A. Mantovani, E. Dejana (1989)
Cytokines as communication signals between leukocytes and endothelial cells.Immunology today, 10 11
-
S. Naylor, P. Gray, P. Lalley (1984)
Mouse immune interferon (IFN-γ) gene is on chromosome 10Somatic Cell and Molecular Genetics, 10
-
T. Mosmann, R. Coffman (1989)
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.Annual review of immunology, 7
-
K. Cantell, H. Schellekens, L. Pyhälä, S. Hirvonen, P. Meide, A. Reus (1986)
Pharmacokinetic Studies with Human and Rat Interferons-γ in Different SpeciesJournal of interferon research, 6
-
J. Trent, S. Olson, R. Lawn (1982)
Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.Proceedings of the National Academy of Sciences of the United States of America, 79 24
-
J. Pober, M. Gimbrone, L. Lapierre, D. Mendrick, W. Fiers, R. Rothlein, T. Springer (1986)
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.Journal of immunology, 137 6
-
R. Schreiber, L. Hicks, A. Celada, N. Buchmeier, P. Gray (1985)
Monoclonal antibodies to murine gamma-interferon which differentially modulate macrophage activation and antiviral activity.Journal of immunology, 134 3
-
D. Yphantis, T. Arakawa (1987)
Sedimentation equilibrium measurements of recombinant DNA derived human interferon gamma.Biochemistry, 26 17
-
Alexander Rabinovitch, H. Baquerizo, C. Pukel, W. Sumoski (1989)
Effects of cytokines on rat pancreatic islet cell monolayer cultures: distinction between functional and cytotoxic effects on islet beta-cells.Regional immunology, 2 2
-
T. Munakata, U. Semba, Y. Shibuya, K. Kuwano, M. Akagi, S. Arai (1985)
Induction of interferon-gamma production by human natural killer cells stimulated by hydrogen peroxide.Journal of immunology, 134 4
-
S. Wolf, P. Temple, Michiko Kobayashi, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R. Hewick (1991)
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.Journal of immunology, 146 9
-
Chaim Jacob, P. Meide, Hugh Mcdevitt, H Shepard, J. Exp (1987)
In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferonThe Journal of Experimental Medicine, 166
-
J. Vilček, D. Henriksen‐Destefano, D. Siegel, A. Klion, R. Robb, J. Le (1985)
Regulation of IFN-gamma induction in human peripheral blood cells by exogenous and endogenously produced interleukin 2.Journal of immunology, 135 3
-
J. Youngner, S. Salvin (1973)
Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.Journal of immunology, 111 6
-
A. Celada, M. Klemsz, R. Maki (1989)
Interferon‐γ activates multiple pathways to regulate the expression of the genes for major histocompatibility class II I‐Aβ, tumor necrosis factor and complement component C3 in mouse macrophagesEuropean Journal of Immunology, 19
-
A. Billiau, H. Heremans, F. Vandekerckhove, R. Dijkmans, H. Sobis, E. Meulepas, H. Carton (1988)
Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.Journal of immunology, 140 5
-
H. Panitch, A. Haley, R. Hirsch, K. Johnson (1987)
EXACERBATIONS OF MULTIPLE SCLEROSIS IN PATIENTS TREATED WITH GAMMA INTERFERONThe Lancet, 329
-
N. Sarvetnick, D. Liggitt, S. Pitts, S. Hansen, T. Stewart (1988)
Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gammaCell, 52
-
F. Letourneur, R. Klausner (1992)
A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chainsCell, 69
-
R. Strunk, F. Cole, D. Perlmutter, H. Colten (1985)
gamma-Interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes.The Journal of biological chemistry, 260 28
-
Karl Johnson, S. Kornfeld (1992)
A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.The Journal of biological chemistry, 267 24
-
Janice Wherry, Robert Schreiber, Emil Unanue (1991)
Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuliInfection and Immunity, 59
-
M. Fountoulakis, J. Juranville, A. Maris, Laurence Ozmen, G. Garotta (1990)
One interferon gamma receptor binds one interferon gamma dimer.The Journal of biological chemistry, 265 32
-
M. Fountoulakis, J. Juranville, Dietrich Stüber, E. Weibel, G. Garotta (1990)
Purification and biochemical characterization of a soluble human interferon gamma receptor expressed in Escherichia coli.The Journal of biological chemistry, 265 22
-
M. Jarpe, H. Johnson (1990)
Topology of receptor binding domains of mouse IFN-gamma.Journal of immunology, 145 10
-
S. Zamvil, P. Nelson, J. Trotter, D. Mitchell, R. Knobler, R. Fritz, L. Steinman (1985)
T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelinationNature, 317
-
M. Aguet (1990)
The interferon-gamma receptor: a comparison with other cytokine receptors.Journal of interferon research, 10 6
-
Q. Xie, H. Cho, J. Calaycay, R. Mumford, K. Swiderek, Terry Lee, A. Ding, Tiffany Troso, C. Nathan (1992)
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.Science, 256 5054
-
V. Jung, Carol Jones, A. Rashidbaigi, D. Geyer, H. Morse, R. Wright, S. Pestka (1988)
Chromosome mapping of biological pathways by fluorescence-activated cell sorting and cell fusion: Human interferon gamma receptor as a model systemSomatic Cell and Molecular Genetics, 14
-
D. Fiorentino, A. Zlotnik, P. Vieira, T. Mosmann, M. Howard, K. Moore, A. O’Garra (1991)
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.Journal of immunology, 146 10
-
C. Mao, G. Merlin, R. Ballotti, M. Metzler, M. Aguet (1990)
Rapid increase of the human IFN-gamma receptor phosphorylation in response to human IFN-gamma and phorbol myristate acetate. Involvement of different serine/threonine kinases.Journal of immunology, 145 12
-
M. Aguet, Z. Dembić, G. Merlin (1988)
Molecular cloning and expression of the human interferon-γ receptorCell, 55
-
W. Farrar, M. Birchenall-Sparks, H. Young (1986)
Interleukin 2 induction of interferon-gamma mRNA synthesis.Journal of immunology, 137 12
-
K. Handa, R. Suzuki, H. Matsui, Y. Shimizu, K. Kumagai (1983)
Natural killer (NK) cells as a responder to interleukin 2 (IL 2). II. IL 2-induced interferon gamma production.Journal of immunology, 130 2
-
Sidney Pestka, J. Langer, K. Zoon, Charles Samuel (1987)
Interferons and their actions.Annual review of biochemistry, 56
-
G. Bancroft, M. Bosma, G. Bosma, E. Unanue (1986)
Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism.Journal of immunology, 137 1
-
F. Heinzel (1990)
The role of IFN-gamma in the pathology of experimental endotoxemia.Journal of immunology, 145 9
-
A. Stern, F. Podlaski, J. Hulmes, Y. Pan, Phyllis QUINNt, Aimee WOLITZKYf, P. Familletti, D. Stremlo, Terri Truitt, R. Chizzonite, Maurice GATELYt (1990)
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.Proceedings of the National Academy of Sciences of the United States of America, 87 17
-
K. Henco, J. Brosius, A. Fujisawa, J. Fujisawa, J. Haynes, J. Hochstadt, T. Kovacic, M. Pašek, A. Schamboeck, J. Schmid (1985)
Structural relationship of human interferon alpha genes and pseudogenes.Journal of molecular biology, 185 2
-
P. Gray, D. Goeddel (1982)
Structure of the human immune interferon geneNature, 298
-
D. Finbloom, D. Hoover, L. Wahl (1985)
The characteristics of binding of human recombinant interferon-gamma to its receptor on human monocytes and human monocyte-like cell lines.Journal of immunology, 135 1
-
M. Lipton, J. Freund (1953)
Allergic encephalomyelitis in the rat induced by the intracutaneous injection of central nervous system tissue and adjuvants.Journal of immunology, 71 2
-
S. Chan, Michiko Kobayashi, D. Santoli, B. Perussia, G. Trinchieri (1992)
Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12). Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2.Journal of immunology, 148 1
-
A. Billiau (1987)
Interferons and inflammation.Journal of interferon research, 7 5
-
Hanna Kelkers, Junming Le, Berish Rubinjll, Yum Yips, Cathryn NaglerSII, Jan VilGekS (1984)
Three molecular weight forms of natural human interferon-gamma revealed by immunoprecipitation with monoclonal antibody.The Journal of biological chemistry, 259 7
-
C. Jacob, Hugh Mcdevitt (1988)
Tumour necrosis factor-α in murine autoimmune 'lupus' nephritisNature, 331
-
T. Arakawa, Y. Hsu, D. Yphantis (1987)
Acid unfolding and self-association of recombinant Escherichia coli derived human interferon gamma.Biochemistry, 26 17
-
M. Langford, D. Weigent, T. Chan, H. Johnson, G. Stanton (1987)
Antibodies to the carboxyl terminus of mouse interferon-gamma neutralize its immunoregulatory and antiviral activities.Journal of interferon research, 7 1
-
Wheelock Ef (1965)
Interferon-like virus-inhibitor induced in human leukocytes by phytohemagglutinin.Science, 149
-
T. Chang, S. McKinney, V. Liu, P. Kung, J. Vilček, J. Le (1984)
Use of monoclonal antibodies as sensitive and specific probes for biologically active human gamma-interferon.Proceedings of the National Academy of Sciences of the United States of America, 81 16
-
B. Beutler, A. Cerami (1986)
Cachectin and tumour necrosis factor as two sides of the same biological coinNature, 320
-
D. Fiorentino, M. Bond, T. Mosmann (1989)
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clonesThe Journal of Experimental Medicine, 170
-
P. Hart, G. Whitty, D. Piccoli, John Hamilton (1989)
Control by IFN-gamma and PGE2 of TNF alpha and IL-1 production by human monocytes.Immunology, 66 3
-
D. Erbe, J. Collins, Lilian Shen, R. Graziano, M. Fanger (1990)
The effect of cytokines on the expression and function of Fc receptors for IgG on human myeloid cells.Molecular immunology, 27 1
-
L. Glimcher, C. Kara (1992)
Sequences and factors: a guide to MHC class-II transcription.Annual review of immunology, 10
-
H. Movat, C. Burrowes, M. Cybulsky, C. Dinarello (1987)
Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury.The American journal of pathology, 129 3
-
J. Wright, P. Lacy, E. Unanue, C. Muszynski, V. Hauptfeld (1986)
Interferon-Mediated Induction of la Antigen Expression on Isolated Murine Whole Islets and Dispersed Islet CellsDiabetes, 35
-
D. Finbloom (1991)
Regulation of cell-surface receptors for human interferon-gamma on the human histiocytic lymphoma cell line U937.The Biochemical journal, 274 ( Pt 3)
-
I. Fidler, W. Fogler, E. Kleinerman, I. Saiki (1985)
Abrogation of species specificity for activation of tumoricidal properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes.Journal of immunology, 135 6
-
Catherine Mao, Michel Aguet, Gilles Merlin (1989)
Molecular characterization of the human interferon-gamma receptor: analysis of polymorphism and glycosylation.Journal of interferon research, 9 6
-
I. Rutenfranz, H. Kirchner (1988)
Pharmacokinetics of Recombinant Murine Interferon-γ in MiceJournal of interferon research, 8
-
H. Johnson, J. Russell, B. Torres (1986)
Second messenger role of arachidonic acid and its metabolites in interferon-gamma production.Journal of immunology, 137 10
-
R. Pujol-Borrell, I. Todd, M. Doshi, G. Bottazzo, R. Sutton, D. Gary, G. Adolf, M. Feldmann (1987)
HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxinNature, 326
-
T. Arakawa, T. Horan, M. McGinley, M. Rohde (1990)
Effect of amino-terminal processing by Staphylococcus aureus V-8 protease on activity and structure of recombinant human interferon-γJournal of interferon research, 10
-
T. Basham, T. Merigan (1983)
Recombinant interferon-gamma increases HLA-DR synthesis and expression.Journal of immunology, 130 4
-
Mitali Basu, Judith Pace, David Pinson, Mark Hayes, Paul Trotta, Stephen Russell (1988)
Purification and partial characterization of a receptor protein for mouse interferon gamma.Proceedings of the National Academy of Sciences of the United States of America, 85 17
-
M. Howard, A. O’Garra (1992)
Biological properties of interleukin 10.Immunology today, 13 6
-
R. Schreiber, J. Pace, S. Russell, A. Altman, D. Katz (1983)
Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon.Journal of immunology, 131 2
-
J. Corbett, Jack Lancaster, M. Sweetland, M. McDaniel (1991)
Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion.The Journal of biological chemistry, 266 32
-
V. Ciccarone, J. Chrivia, K. Hardy, H. Young (1990)
Identification of enhancer-like elements in human IFN-gamma genomic DNA.Journal of immunology, 144 2
-
J. Pace, S. Russell, R. Schreiber, A. Altman, D. Katz (1983)
Macrophage activation: priming activity from a T-cell hybridoma is attributable to interferon-gamma.Proceedings of the National Academy of Sciences of the United States of America, 80 12
-
F. Liew, S. Millott, Claire Parkinson, R. Palmer, S. Moncada (1990)
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.Journal of immunology, 144 12
-
Fooyew Liew, Y. Li, S. Millott (1990)
Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide.Journal of immunology, 145 12
-
J. Chrivia, T. Wedrychowicz, H. Young, K. Hardy (1990)
A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytesThe Journal of Experimental Medicine, 172
-
G. Bancroft, K. Sheehan, Robert Schreiber, Emil Unanue (1989)
Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice.Journal of immunology, 143 1
-
B. Aggarwal, T. Eessalu (1987)
Induction of receptors for tumor necrosis factor-alpha by interferons is not a major mechanism for their synergistic cytotoxic response.The Journal of biological chemistry, 262 21
-
R. Derynck, D. Leung, P. Gray, D. Goeddel (1982)
Human Interferon γ is encoded by a single class of mRNANucleic Acids Research, 10
-
Thomas Gajewskj, S. Schell, G. Nau, F. Fitch (1989)
Regulation of T‐Cell Activation; Differences among T‐Cell SubsetsImmunological Reviews, 111
-
L. Old (1988)
Tumor necrosis factor.Clinical bulletin, 6 3
-
S. Somers, J. Weiel, T. Hamilton, D. Adams (1986)
Phorbol esters and calcium ionophore can prime murine peritoneal macrophages for tumor cell destruction.Journal of immunology, 136 11
-
F. Cofano, S. Moore, Shoichiro Tanaka, N. Yuhki, S. Landolfo, E. Appella (1990)
Affinity purification, peptide analysis, and cDNA sequence of the mouse interferon gamma receptor.The Journal of biological chemistry, 265 7
-
K. Nagata, T. Izumi, T. Kitagawa, N. Yoshida (1987)
Oligomeric structure of recombinant human and murine immune interferons by means of sedimentation equilibrium.Journal of interferon research, 7 3
-
N. Ruddle, C. Bergman, Katherine McGrath, E. Lingenheld, Margaret Grunnet, Steven Padula, Robert Clark (1990)
An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitisThe Journal of Experimental Medicine, 172
-
D. Novick, P. Orchansky, M. Revel, M. Rubinstein (1987)
The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies.The Journal of biological chemistry, 262 18
-
H. Hogrefe, P. Mcphie, J. Bekisz, J. Enterline, D. Dyer, D. Webb, T. Gerrard, K. Zoon (1989)
Amino terminus is essential to the structural integrity of recombinant human interferon-gamma.The Journal of biological chemistry, 264 21
-
P. Anderson, Y. Yip, J. Vilček (1983)
Human interferon-gamma is internalized and degraded by cultured fibroblasts.The Journal of biological chemistry, 258 10
-
T. Kasahara, J. Hooks, S. Dougherty, J. Oppenheim (1983)
Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets.Journal of immunology, 130 4
-
J. Mond, J. Carman, C. Sarma, J. Ohara, F. Finkelman (1986)
Interferon-gamma suppresses B cell stimulation factor (BSF-1) induction of class II MHC determinants on B cells.Journal of immunology, 137 11
-
D. Caput, B. Beutler, K. Hartog, R. Thayer, S. Brown‐Shimer, A. Cerami (1986)
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.Proceedings of the National Academy of Sciences of the United States of America, 83 6
-
E. Rinderknecht, B. O'Connor, H. Rodriguez (1984)
Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation.The Journal of biological chemistry, 259 11
-
Shaun Scahill, Rene Devos, Jose Van, Der, Heyden, Walter Fiers (1983)
Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells.Proceedings of the National Academy of Sciences of the United States of America, 80 15
- Publisher
- Annual Reviews
- Copyright
- Copyright 1993 Annual Reviews. All rights reserved
- Subject
- Review Articles
- ISSN
- 0732-0582
- eISSN
- 1545-3278
- DOI
- 10.1146/annurev.iy.11.040193.003035
- pmid
- 8476573
- Publisher site
- See Article on Publisher Site
Abstract
The last ten years have seen an explosive growth in our understanding of IFNI" The cloning of the cDNAs for IFNI' and its receptor have made available large amounts of highly purified recombinant IFNI' and soluble IFNI' receptor. In addition, highly specific neutralizing monoclonal anti bodies have been generated to both of these proteins. Using these reagents, IFNI' and the IFNI' receptor have been characterized on a molecular basis. Structure-function studies carried out on these proteins have identified key molecular regions that are required for biologic activity. Moreover, a great deal is now known concerning the physiologic role that IFNy plays in vivo. In this review we focus on the new developments in the areas of IFNy biochemistry and biology and pay particular attention to the IFNI' receptor and three aspects of IFNI' biology that are of special interest to immun ologists: host defense, inflammation, and autoimmunity. INTRODUCTION Interferon-gamma (IFNI') was first recognized nearly 30 years ago on the basis of its antiviral activity ( 1 ) . During the ensuing years, a great deal of information has accumulated which unequivocally establishes that this pleotropic cytokine plays an important role in modulating nearly all phases of immune and
Journal
Annual Review of Immunology – Annual Reviews
Published: Apr 1, 1993