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By D. W. WATSON2 AND C. A. BRANDLY Departments o Agricultural Bacteriology and Veterinary Science f University o Wisconsin, M f adison 6, Wisconsin The complex phenomenon encompassing virulence and patho genicity is difficult to treat as a yearly review. The subject, if de fined as an expression or interaction of the host-parasite relation ship, has so many components that an adequate survey of all pa pers pertinent thereto would be impossible within the space allotted. This review will include not only studies dealing with the various factors associated with the parasite as they apparently influence virulence but also those pertaining to the several proper ties of the host which are equally important for an analysis of the problem. Material has been selected from the various fields of bacteriology and virology to illustrate the general methods and trends in current investigations. Many phases of the subject have been reviewed in the first and second volumes of the Annual Review of Microbiology. Within recent years several reviews have appeared; Dubos (1) in his ex cellent treatise on the "Bacterial Cell" has presented a lucid chap ter on the nature of virulence; the various mechanisms of patho genicity and virulence
Annual Review of Microbiology – Annual Reviews
Published: Oct 1, 1949
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