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The first original paper in this issue is by Frackrell, Kirby, Sanghera and Hartley, who undertake a study into the effect of silver sulfadiazine and zinc oxide creams on dose distribution during radiotherapy. The use of metallic containing creams to prevent and treat radiodermatitis is controversial and lacking evidence base. The authors compare the dose effect of two metallic based skin creams, which could be used for treating radiodermatitis, to a control. Universal containers of Silver Sulfadiazine cream, zinc oxide cream and aqueous cream were examined using a CT scanner to assess their electron densities relative to water. Secondly, each cream was exposed to 100 kV and 6 MV photons. The relative doses were measured using an X-ray chamber. The results found the relative electron density measured was similar for the silver sulfadiazine and aqueous creams. Zinc Oxide was 40% higher. The relative dose measurements showed that Silver Sulfadiazine behaved in a similar way to aqueous cream However, zinc oxide cream exhibited a dose difference of 11·0% in kV photons and −4·1% in MV photons. The authors concluded that the application of Silver Sulfadiazine appears unlikely to bring about significant changes in the dose distribution when compared to aqueous
Journal of Radiotherapy in Practice – Cambridge University Press
Published: Apr 23, 2015
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