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To start this issue, there is a guest editorial by Moallim, Maungwe and Chamunyonga, who discuss the use of cone beam computed tomography (CBCT) guided radiotherapy for locally advanced head and neck cancer. The authors consider the dosimetric impact of weight loss on volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) plans for selected organs at risk structures (OARs). It is common for head and neck patients to be affected by time trend errors as a result of weight loss during a course of radiation treatment. The objective of this planning study was to investigate the impact of weight loss on VMAT as well as IMRT for locally advanced head and neck cancer using automatic co-registration of the CBCT. The authors undertook a retrospective analysis of previously treated IMRT plans for 10 patients, with locally advanced head and neck cancer. A VMAT plan was also produced for all patients. They calculated the dose-volume histograms (DVH) indices for spinal cord planning at risk volumes (PRVs), the brainstem PRVs (SC+0.5cm and BS+0.5cm, respectively) as well as mean dose to the parotid glands. This study demonstrated a clinically significant impact of weight loss on DVH indices analysed in head
Journal of Radiotherapy in Practice – Cambridge University Press
Published: Nov 4, 2015
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