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Bronchial Asthma: Current Trends in Treatment

Bronchial Asthma: Current Trends in Treatment AbstractAsthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic (intrinsic) types, while patients with allergic type responded better to corticosteroids. Since 2013 the definition of asthma has changed. Recently, better insight into clinical consi -derations and underlying inflammatory phenotypes has been gained. Defining these phenotypes has already led to more specific clinical trials and, therefore, to more personalized and successfully targeted therapy. For future, much more effort is put in identifying new phenotype-specific biomarkers which could be helpful in stratification of heterogeneous patients with asthma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Medica Martiniana de Gruyter

Bronchial Asthma: Current Trends in Treatment

Palova, R; Adamcakova, J; Mokra, D; Mokry, J
Acta Medica Martiniana , Volume 20 (1): 9 – Apr 1, 2020
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Publisher
de Gruyter
Copyright
© 2020 R Palova et al., published by Sciendo
ISSN
1335-8421
eISSN
1338-4139
DOI
10.2478/acm-2020-0002
Publisher site
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Abstract

AbstractAsthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic (intrinsic) types, while patients with allergic type responded better to corticosteroids. Since 2013 the definition of asthma has changed. Recently, better insight into clinical consi -derations and underlying inflammatory phenotypes has been gained. Defining these phenotypes has already led to more specific clinical trials and, therefore, to more personalized and successfully targeted therapy. For future, much more effort is put in identifying new phenotype-specific biomarkers which could be helpful in stratification of heterogeneous patients with asthma.

Journal

Acta Medica Martiniana – de Gruyter

Published: Apr 1, 2020

Keywords: bronchial asthma; asthma phenotypes; asthma therapy

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