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A RARE DISEASE OF THE BREAST: BOWEN’S DISEASE -The Journal of medical research, 4
- Publisher
- Karger
- Copyright
- © 2018 The Author(s). Published by S. Karger AG, Basel
- eISSN
- 1662-6575
- DOI
- 10.1159/000492382
- Publisher site
- See Article on Publisher Site
Abstract
Bowen’s disease is a type of intraepidermal squamous cell carcinoma that commonly develops in areas of the skin exposed to sunlight, such as the scalp, trunk, and limbs. Although development of Bowen’s disease in other sites, such as the nipple, is extremely rare, we herein report our experience with one such case. A 76-year-old female presented to our hospital with complaints of right nipple pruritus. We diagnosed Bowen’s disease via nipple skin biopsy, and the patient underwent right nipple resection. The deep tissue margin was positive for malignancy; therefore, the patient subsequently underwent right partial mastectomy. Histopathology revealed tumor cells inside the lactiferous ducts, but the resection margin was negative for malignancy. Bowen’s disease of the nipple may progress from the skin to the lactiferous ducts. Clinical findings can be used to evaluate lesion progression and determine the necessary extent of skin and mammary gland resection.
Journal
Case Reports in Oncology – Karger
Published: Jan 1, 2018
Keywords: Bowen’s disease; Squamous cell carcinoma; Nipple; Breast cancer