Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/karger/immunotherapy-for-recurrent-urinary-tract-infections-effects-of-an-7ZAxJRvXLi
References (40)
-
(2004)
Immunotherapy with an oral bacterial extract for urinary tract infections -
K. Naber, Yong‐Hyun Cho, Tetsurou Matsumoto, A. Schaeffer (2009)
Immunoactive prophylaxis of recurrent urinary tract infections: a meta-analysis.International journal of antimicrobial agents, 33 2
-
B. Lettgen (1996)
PREVENTION OF RECURRENT URINARY TRACT INFECTIONS IN FEMALE CHILDREN OM-89 Immunotherapy Compared with Nitrofurantoin Prophylaxis in a Randomized Pilot StudyCurrent Therapeutic Research-clinical and Experimental, 57
-
B. Foxman (2002)
Epidemiology of urinary tract infections: incidence, morbidity, and economic costs.The American journal of medicine, 113 Suppl 1A
-
E. Comploj, M. Koen, T. Becker, C. Berger, Katharina Mitter, M. Riccabona (2009)
Does A Preoperative Percutaneous Nephrostomy Influence the Outcome of Pyeloplasty in Infants and ChildrenJournal of Pediatric Urology, 5
-
Silvia Schmidhammer, R. Ramoner, L. Höltl, G. Bartsch, M. Thurnher, C. Zelle-Rieser (2002)
An Escherichia coli-based oral vaccine against urinary tract infections potently activates human dendritic cells.Urology, 60 3
-
(1991)
The immunomodulators Broncho - Vaxom and Uro - Vaxom stimulate the bacterial killing and oxidative metabolism of polymorphonuclear leukocytes by the activation of phosphatidylinositol turnover -
C. Shaw, R. Matthews, S. Perry, K. Williams, N. Spiers, R. Assassa, C. McGrother, H. Dallosso, Carol Jagger, C. Mayne, M. Clarke (2004)
Validity and reliability of a questionnaire to measure the impact of lower urinary tract symptoms on quality of life: The Leicester impact scaleNeurourology and Urodynamics, 23
-
(2002)
urinary tract infections potently activates human dendritic cells -
Claude Schulman, A. Corbusier, H. Michiels, H. Taenzer (1993)
Oral immunotherapy of recurrent urinary tract infections: a double-blind placebo-controlled multicenter study.The Journal of urology, 150 3
-
Albert Bosch, Vicente Benedí, Ramon Pares, Juan Jofre (1988)
Enhancement of the humoral immune response and resistance to bacterial infection in mice by the oral administration of a bacterial immunomodulator (OM-89).Immunopharmacology and immunotoxicology, 10 3
-
E. Rugendorff (1992)
Immunological therapy of recurrent urinary tract infections with immunoactive E. coll fractions in womenInternational Urogynecology Journal, 3
-
M. Huber, K. Krauter, G. Winkelmann, H.W Bauer, V.W Rahlfs, P.A Lauener, G. Blessmann, W. Bessler (2000)
Immunostimulation by bacterial components: II. Efficacy studies and meta-analysis of the bacterial extract OM-89.International journal of immunopharmacology, 22 12
-
J. Krieger (2002)
Urinary tract infections: what's new?The Journal of urology, 168 6
-
M. Czerwionka-Szaflarska, Małgorzata Pawłowska (1996)
Influence of Uro-Vaxom on sIgA level in urine in children with recurrent urinary tract infections.Archivum immunologiae et therapiae experimentalis, 44 2-3
-
H. Tammen (1990)
Immunobiotherapy with Uro-Vaxom in recurrent urinary tract infection. The German Urinary Tract Infection Study Group.British journal of urology, 65 1
-
K. Naber, B. Bergman, M. Bishop, T. Bjerklund-Johansen, H. Botto, B. Lobel, F. Cruz, F. Selvaggi (2001)
EAU guidelines for the management of urinary and male genital tract infections. Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU).European urology, 40 5
-
H. Bauer, S. Alloussi, G. Egger, H. Blümlein, G. Cozma, C. Schulman (2005)
A long-term, multicenter, double-blind study of an Escherichia coli extract (OM-89) in female patients with recurrent urinary tract infections.European urology, 47 4
-
Seung-ju Lee, S. Kim, Yong‐Hyun Cho, Y. Woo, B. Kim, Sung‐Goo Chang, Min Kim, C. Kim, J. Lee, B. Sim, H. Kim, B. Chung, I. Cho, Sang Lee (2007)
Efficacy and Safety of Uro-Vaxom Treatment for Patients with Recurrent Cystitis: An Open Multicenter StudyKorean Journal of Urology, 48
-
C. Bottex, A. Martín, R. Fontanges (1990)
Action of a mycotoxin (diacetoxyscirpenol) on the immune response of the mouse--interaction with an immunomodulator (OM-89).Immunopharmacology and immunotoxicology, 12 2
-
(1984)
Effect of antimicrobial agents on the immune response -
C. Frey, W. Obolensky, H. Wyss (1986)
Treatment of recurrent urinary tract infections: efficacy of an orally administered biological response modifier.Urologia internationalis, 41 6
-
A. Pigné, F. Valentini, P. Nelson (2009)
Comparison at Short Follow-Up of the Changes in the Voiding Phase Induced by Sub-Urethral Tapes Using a Mathematical Micturition ModelCurrent Urology, 3
-
G. Kahlmeter (2003)
An international survey of the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS Project.The Journal of antimicrobial chemotherapy, 51 1
-
Guidelines on the management of urinary and male genital tract infections -
(1993)
placebo-controlled multicenter study -
(1989)
Efficacy of an immunomodulator in compensating antibiotic-induced immunosuppression -
H. Tammen, C. Frey (2000)
Treatment of Recurrent Urinary Tract Infections with Uro-Vaxom @ Open Multicenter Study with 521 Patients -
G. Popa, K. Lauber, H. Rothe, E. Rugendorff (1996)
REZIDIVIERENDE HARNWEGSINFEKTIONEN IN DER POSTMENOPAUSE: WIRKSAMKEIT EINERORALEN IMMUNTHERAPIE MIT E.-COLI-FRAKTIONENMünchener medizinische Wochenschrift, 138
-
H. Hachen (1990)
Oral immunotherapy in paraplegic patients with chronic urinary tract infections: a double-blind, placebo-controlled trial.The Journal of urology, 143 4
-
R. Baertschi, J. Balmer, S. Eduah, A. Liechti, D. Lurie, H. Schams (2003)
Bacterial extract for the prevention of recurrent urinary tract infections in pregnant women: A pilot studyInternational Journal of Immunotherapy, 19
-
P. Magasi, J. Pánovics, Árpád Illés, M. Nagy (1994)
Uro-Vaxom and the management of recurrent urinary tract infection in adults: a randomized multicenter double-blind trial.European urology, 26 2
-
Huston Gj (1987)
The Hospital Anxiety and Depression Scale.The Journal of rheumatology, 14 3
-
L. Freedman (1975)
Natural history of urinary infection in adults.Kidney international. Supplement, 4
-
(2000)
Zelle-Rieser C: An Escherichia coli-based oral vaccine -
(1990)
Neuer Therapieansatz bei re - zidivierenden Harnwegsinfekten -
(1992)
Rezidivprophylaxe des weiblichen Harnwegsinfektes. Ergebnis einer Phase-IV Studie mit UroVaxom -
(1984)
microbial agents on the immune response; in: Rusticcia AM, Cunha BA (eds): Antimicrobial therapy -
Seung-ju Lee, S. Kim, Yong‐Hyun Cho, M. Yoon (2006)
Anti-inflammatory effect of an Escherichia coli extract in a mouse model of lipopolysaccharide-induced cystitisWorld Journal of Urology, 24
-
(1992)
Ergebnis einer Phase-IV Studie mit Uro-Vaxom
- Publisher
- Karger
- Copyright
- © 2009 S. Karger AG, Basel
- ISSN
- 1661-7649
- eISSN
- 1661-7657
- DOI
- 10.1159/000189674
- Publisher site
- See Article on Publisher Site
Abstract
The burden of urinary tract infections (UTIs) is high in both industrialized and developing countries. As causative therapies of these frequently recurring infections have substantial limits, preventive measures deserve priority. Among these, immunostimulation with bacterial extracts has been shown to prevent recurrent UTIs and to be very safe. The aim of this review is to focus on the immunostimulating agent OM-89, a biotechnology-derived lyophilized extract from Escherichia coli, a germ frequently responsible for UTIs, and formulated for oral administration. This review will cover its pharmacological effects and its actions in clinical practice with respect to both efficacy and safety. A particular emphasis will be put on clinical trials conducted in children, adults and special patient populations as well as on a survey assessing the effect of OM-89 on the patients’ quality of life.
Journal
Current Urology – Karger
Published: Jan 1, 2009
Keywords: Bacterial extract;