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Intravesical instillation of Bacillus Calmette-Guerin (BCG) is the most commonly used immunotherapeutic adjuvant therapy for superficial bladder carcinoma. BCG is a live attenuated vaccine of Mycobacterium bovus which has been shown to decrease tumor recurrence rate, delay tumor progression, and improve overall survival. Intravesical BCG is well tolerated, with a complication rate under 5%. A literature review revealed tuberculous epididymitis to be a rare adverse event following intravesical BCG therapy. We report the case of an 82-year-old male undergoing BCG therapy for superficial transitional cell carcinoma of the bladder who presented with a painless right testicular mass. The patient had no previous history of tuberculosis. He successfully underwent a right orchiectomy and histopathology confirmed M. bovis as the etiological agent.
Current Urology – Karger
Published: Jan 1, 2011
Keywords: Bacillus Calmette-Guerin; Bladder cancer; Tuberculous epididymitis
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